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Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020
Summary Of Significant Accounting Policies [Line Items] |  |
Stock based compensation expenses | $ 10,774 | $ 6,829
Weighted average fair value of stock option granted | $ 2.62 | $ 2.15
Asset Impairment Charges | $ 740 | $ 0
Operating Lease Impairment Loss | 600 |
Collaboration revenue | 398 | 0
Accumulated deficit | $ (842,852) | (764,101)
Office and computer equipment |  |
Summary Of Significant Accounting Policies [Line Items] |  |
Property and equipment useful life | 3 years |
Software |  |
Summary Of Significant Accounting Policies [Line Items] |  |
Property and equipment useful life | 3 years |
Laboratory equipment |  |
Summary Of Significant Accounting Policies [Line Items] |  |
Property and equipment useful life | 5 years |
Leasehold improvements |  |
Summary Of Significant Accounting Policies [Line Items] |  |
Asset Impairment Charges | $ 100 |
Estimated useful life | Life of the lease |
Stock Options |  |
Summary Of Significant Accounting Policies [Line Items] |  |
Stock based compensation expenses | $ 7,400 | 4,300
Restricted Stock |  |
Summary Of Significant Accounting Policies [Line Items] |  |
Stock based compensation expenses | 3,400 | 2,500
Restricted Stock Units (RSUs) [Member] |  |
Summary Of Significant Accounting Policies [Line Items] |  |
Stock based compensation expenses | $ 10,800 | $ 6,800

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