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Warrants - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  |  |  |  | 12 Months Ended
--- | --- | --- | --- | --- | --- | ---
Dec. 28, 2021 | Aug. 06, 2021 | Oct. 22, 2019 | Sep. 12, 2019 | Nov. 11, 2018 | Dec. 31, 2022 | Dec. 31, 2021
Fair Value Assumptions Expected volatility Rate Maximum |  |  |  |  |  | 88.75% | 74.80%
Fair Value Assumptions Risk Free Interest Rate Maximum |  |  |  |  |  | 4.21% | 1.36%
Aggregate offering price |  |  |  |  |  | $ 14,724 |
Proceeds from private placement |  |  |  | $ 52,500 |  |  |
Silicon Valley Bank Loan [Member] |  |  |  |  |  |  |
Warrant Exercise Per share | $ 1.16 | $ 2.22 |  |  |  |  |
Number of warrants issued |  | 432,844 |  |  |  |  |
MD Anderson Warrant [Member] |  |  |  |  |  |  |
Number of securities into which the class of warrant converted |  |  | 3,333,333 |  |  |  |
Warrant Exercise Per share |  |  | $ 0.001 |  |  |  |
Fair Value of Warrants |  |  | $ 14,500 |  |  |  |
Warrant Expiry date |  |  | Dec. 31, 2026 |  |  |  |
Svb Warrants [Member] |  |  |  |  |  |  |
Common stock |  | 432,844 |  |  |  |  |
Exercise price |  | 2.22 |  |  |  |  |
Warrants fully vested upon issuance |  | 10 years |  |  |  |  |
Black-Scholes Model [Member] | Silicon Valley Bank Loan [Member] |  |  |  |  |  |  |
Fair Value Assumptions Expected Term1 | 10 years |  |  |  |  |  |
Exercise price | 1.16 |  |  |  |  |  |
Expected volatility | 81.00% |  |  |  |  |  |
Risk-free interest rate | 1.49% |  |  |  |  |  |
Number of warrants issued | 649,615 |  |  |  |  |  |
Dividends | $ 0 |  |  |  |  |  |
Fair Value, Liability, Recurring Basis, Unobservable Input Reconciliation, Gain (Loss), Statement of Income or Comprehensive Income [Extensible Enumeration] |  |  |  |  |  |  | Other Nonoperating Income (Expense)
Change in fair value |  |  |  |  |  |  | $ 200
Black-Scholes Model [Member] | Svb Warrants [Member] |  |  |  |  |  |  |
Fair Value of Warrants |  | $ 800 |  |  |  |  |
Fair Value Assumptions Expected Term1 |  | 10 years |  |  |  |  |
Expected volatility |  | 79.00% |  |  |  |  |
Risk-free interest rate |  | 1.31% |  |  |  |  |
Dividends |  | $ 0 |  |  |  |  |
Securities Purchase Agreement [Member] |  |  |  |  |  |  |
Aggregate offering price |  |  |  |  | $ 47,100 |  |
Private Placement [Member] |  |  |  |  |  |  |
Number of securities into which the class of warrant converted |  |  |  | 17,803,031 | 18,939,394 |  |
Warrant Exercise Per share |  |  |  | $ 3.01 | $ 3.01 |  |
Fair Value Assumptions Expected volatility Rate Maximum |  |  |  |  | 71.00% |  |
Fair Value Assumptions Risk Free Interest Rate Maximum |  |  |  |  | 2.99% |  |
Fair Value Assumptions Expected Term1 |  |  |  |  | 5 years |  |
Placement agent fees and other expenses |  |  |  | $ 1,100 |  |  |
Fair value of adjustment of warrants |  |  |  |  | $ 18,400 |  |
Dividends |  |  |  |  | $ 0 |  |
Private Placement [Member] | New Warrants [Member] |  |  |  |  |  |  |
Number of securities into which the class of warrant converted |  |  |  | 17,803,031 |  |  |
Warrant Exercise Per share |  |  |  | $ 7.00 |  |  |
Non-cash inducement warrant expense |  |  |  | $ 60,800 |  |  |

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- Definition Non Operating Income Expense Inducement Of Warrants. + References No definition available. + Details
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- Definition Exercise price per share or per unit of warrants or rights outstanding. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 3 -URI https://asc.fasb.org/extlink&oid=126973232&loc=d3e21475-112644 + Details
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- Definition Number of securities into which each warrant or right may be converted. For example, but not limited to, each warrant may be converted into two shares. + References No definition available. + Details
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- Definition Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 3 -URI https://asc.fasb.org/extlink&oid=126973232&loc=d3e21475-112644 + Details
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- Definition Describe the call and/or exercise rights, prices and dates of common stock. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 3 -URI https://asc.fasb.org/extlink&oid=126973232&loc=d3e21475-112644 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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- Definition Amount of common stock allocated to investors to buy shares of a new issue of common stock before they are offered to the public. When stock is sold on a subscription basis, the issuer does not initially receive the total proceeds. In general, the issuer does not issue the shares to the investor until it receives the entire proceeds. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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- Definition Amount of paid and unpaid cash, stock, and paid-in-kind (PIK) dividends declared, for example, but not limited to, common and preferred stock. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.3-04) -URI https://asc.fasb.org/extlink&oid=120397183&loc=d3e187085-122770 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 405 -Section 45 -Paragraph 2 -URI https://asc.fasb.org/extlink&oid=6957935&loc=d3e64057-112817 + Details
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- Definition Amount of expense (income) related to adjustment to fair value of warrant liability. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3602-108585 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 480 -SubTopic 10 -Section 25 -Paragraph 13 -URI https://asc.fasb.org/extlink&oid=109262497&loc=d3e20148-110875 + Details
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- Definition Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI https://asc.fasb.org/extlink&oid=126976982&loc=d3e19207-110258 + Details
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- Definition Indicates line item in statement in which net income is reported that includes gain (loss) from liability measured at fair value using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI https://asc.fasb.org/extlink&oid=126976982&loc=d3e19207-110258 + Details
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- Definition The cash inflow associated with the amount received from entity's raising of capital via private rather than public placement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3255-108585 + Details
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- Definition The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(ii) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition The estimated measure of the maximum percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References No definition available. + Details
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- Definition The risk-free interest rate assumption that is used in valuing an option on its own shares. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iv) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition The maximum risk-free interest rate assumption that is used in valuing an option on its own shares. + References No definition available. + Details
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- Definition Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.3-04) -URI https://asc.fasb.org/extlink&oid=120397183&loc=d3e187085-122770 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 2 -URI https://asc.fasb.org/extlink&oid=126973232&loc=d3e21463-112644 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(28)) -URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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- Definition Expiration date of outstanding warrant and right embodying unconditional obligation requiring redemption by transferring asset at specified or determinable date or upon event certain to occur, in YYYY-MM-DD format. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (bbb)(2) -URI https://asc.fasb.org/extlink&oid=126976982&loc=d3e19207-110258 + Details
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