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Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2023 | Dec. 31, 2022
Income Taxes [Line Items] |  |
Net operating loss carryforwards | $ 148,009 | $ 171,070
Deferred tax assets operating loss carryforwards without expire date | 363,200 |
Research and development credit carryforwards | 39,838 | 40,116
Reduced credits carryforward | 0 |
Uncertain Tax Positions Adjustment | 0 | $ 0
Increase (decrease) in deferred tax assets | (25,800) |
Domestic Tax Authority [Member] |  |
Income Taxes [Line Items] |  |
Net operating loss carryforwards | $ 704,900 |
Net operating loss carryforwards, expiration date | 2037 |
Federal and State [Member] |  |
Income Taxes [Line Items] |  |
Deferred tax assets operating loss carryforwards with expire date | $ 341,700 |
Net operating loss carryforwards, expiration date | 2043 |
Federal and State [Member] | Research Tax Credit Carryforward |  |
Income Taxes [Line Items] |  |
Research and development credit carryforwards | $ 39,800 |
State and Local Jurisdiction [Member] |  |
Income Taxes [Line Items] |  |
Net operating loss carryforwards | 497,900 |
Increase (decrease) in deferred tax assets | $ 0 |

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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 740 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 6 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482685/740-10-50-6 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 8 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482685/740-10-50-8 + Details
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