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v3.25.1

Income Taxes - Significant Component of Deferred Tax Assets (Detail) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Net operating loss carryforwards | $ 154,634 | $ 148,009
Deferred tax assets: |  |
Start-up and pre-clinical studies | 11,011 | 13,754
Research and development credit carryforwards | 40,486 | 39,838
Stock-based compensation | 699 | 681
Capitalized acquisition costs | 1,050 | 1,570
Lease liability | 0 | 0
Depreciation | 1 | 1
Capitalized research expenses | 5,400 | 7,176
Other | 0 | 2
Deferred Tax Assets Gross | 213,281 | 211,031
Less valuation allowance | (213,281) | (211,031)
Total deferred tax assets | 0 | 0
Deferred tax liabilities: |  |
Right-of-use asset | 0 | 0
Total deferred tax liabilities | 0 | 0
Net deferred taxes | $ 0 | $ 0

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