<SEC-DOCUMENT>0001209191-21-035149-index.html : 20210521
<SEC-HEADER>0001209191-21-035149.hdr.sgml : 20210521
<ACCEPTANCE-DATETIME>20210521210855
ACCESSION NUMBER:		0001209191-21-035149
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20210520
FILED AS OF DATE:		20210521
DATE AS OF CHANGE:		20210521

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Muralidhar Bali
		CENTRAL INDEX KEY:			0001784138

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39594
		FILM NUMBER:		21950915

	MAIL ADDRESS:	
		STREET 1:		C/O EXICURE, INC.
		STREET 2:		8045 LAMON AVENUE, SUITE 410
		CITY:			SKOKIE
		STATE:			IL
		ZIP:			60077

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SPRUCE BIOSCIENCES, INC.
		CENTRAL INDEX KEY:			0001683553
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				812154263
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2001 JUNIPERO SERRA BLVD., SUITE 640
		CITY:			DALY CITY
		STATE:			CA
		ZIP:			94104
		BUSINESS PHONE:		(415) 294-1687

	MAIL ADDRESS:	
		STREET 1:		2001 JUNIPERO SERRA BLVD., SUITE 640
		CITY:			DALY CITY
		STATE:			CA
		ZIP:			94104
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
Document 1 - file: doc4.html

Document 1 - RAW XML: doc4.xml

</DOCUMENT>
</SEC-DOCUMENT>