<SEC-DOCUMENT>0001415889-25-020261-index.html : 20250724
<SEC-HEADER>0001415889-25-020261.hdr.sgml : 20250724
<ACCEPTANCE-DATETIME>20250724193027
ACCESSION NUMBER:		0001415889-25-020261
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20250722
FILED AS OF DATE:		20250724
DATE AS OF CHANGE:		20250724

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Muralidhar Bali
		CENTRAL INDEX KEY:			0001784138
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39594
		FILM NUMBER:		251148196

	MAIL ADDRESS:	
		STREET 1:		C/O EXICURE, INC.
		STREET 2:		8045 LAMON AVENUE, SUITE 410
		CITY:			SKOKIE
		STATE:			IL
		ZIP:			60077

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SPRUCE BIOSCIENCES, INC.
		CENTRAL INDEX KEY:			0001683553
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				812154263
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		611 GATEWAY BOULEVARD, SUITE 740
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		(415) 655-4168

	MAIL ADDRESS:	
		STREET 1:		611 GATEWAY BOULEVARD, SUITE 740
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4-07242025_110724.xml
<TEXT>
Document 1 - file: form4-07242025_110724.html

Document 1 - RAW XML: form4-07242025_110724.xml

</DOCUMENT>
</SEC-DOCUMENT>