<SEC-DOCUMENT>0000950170-25-055856-index.html : 20250418
<SEC-HEADER>0000950170-25-055856.hdr.sgml : 20250418
<ACCEPTANCE-DATETIME>20250418160504
ACCESSION NUMBER:		0000950170-25-055856
CONFORMED SUBMISSION TYPE:	PRE 14A
PUBLIC DOCUMENT COUNT:		6
CONFORMED PERIOD OF REPORT:	20250609
FILED AS OF DATE:		20250418
DATE AS OF CHANGE:		20250418

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SPRUCE BIOSCIENCES, INC.
		CENTRAL INDEX KEY:			0001683553
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				812154263
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		PRE 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39594
		FILM NUMBER:		25850471

	BUSINESS ADDRESS:	
		STREET 1:		611 GATEWAY BOULEVARD, SUITE 740
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		(415) 655-4168

	MAIL ADDRESS:	
		STREET 1:		611 GATEWAY BOULEVARD, SUITE 740
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
</SEC-HEADER>
<DOCUMENT>
<TYPE>PRE 14A
<SEQUENCE>1
<FILENAME>sprb-predef14a-2025.htm
<DESCRIPTION>PRE 14A
<TEXT>
Document 1 - file: sprb-predef14a-2025.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>img191538130_0.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: img191538130_0.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>img191538130_1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: img191538130_1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>img191538130_2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: img191538130_2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>img191538130_3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: img191538130_3.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>img191538130_4.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: img191538130_4.jpg

</DOCUMENT>
</SEC-DOCUMENT>