    <SEC-DOCUMENT>0001213900-22-016672-index.html : 20220331
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    <ACCEPTANCE-DATETIME>20220331151111
    ACCESSION NUMBER:		0001213900-22-016672
    CONFORMED SUBMISSION TYPE:	10-K
    PUBLIC DOCUMENT COUNT:		22
    CONFORMED PERIOD OF REPORT:	20211231
    FILED AS OF DATE:		20220331
    DATE AS OF CHANGE:		20220331

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Blue Water Vaccines Inc.
    		CENTRAL INDEX KEY:			0001782107
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		10-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-41294
    		FILM NUMBER:		22791784

    	BUSINESS ADDRESS:
    		STREET 1:		2041 COURTLAND AVENUE
    		CITY:			CINCINNATI
    		STATE:			OH
    		ZIP:			45212
    		BUSINESS PHONE:		646-303-0737

    	MAIL ADDRESS:
    		STREET 1:		2041 COURTLAND AVENUE
    		CITY:			CINCINNATI
    		STATE:			OH
    		ZIP:			45212
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