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Significant Agreements (Details) - USD ($) | 1 Months Ended | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Apr. 20, 2022 | May 21, 2021 | Mar. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Significant Agreements (Details) [Line Items] |  |  |  |  |
OUI Agreement Expiration |  |  | 10 years |  |
Intellectual property licenses is recorded as research and development expenses |  |  | $ 3,000 |  |
Ology Bioservices, Inc [Member] |  |  |  |  |
Significant Agreements (Details) [Line Items] |  |  |  |  |
Aggregate agreement amount initial agreement |  |  | 4,000,000 |  |
Prepaid expenses to remaining prepaid expenses |  |  |  |  | $ 100,000
Prepaid expense remaining |  |  |  |  | $ 48,600
Aggregate amount |  | $ 2,800,000 |  |  |
Cost plus, percentage |  | 15.00% |  |  |
Accounts payable |  |  |  | $ 164,000 |
Accrued expenses |  |  | $ 332,000 | $ 115,000 |
Ology Bioservices, Inc [Member] | Subsequent Event [Member] |  |  |  |  |
Significant Agreements (Details) [Line Items] |  |  |  |  |
Increased in obligation | $ 300,000 |  |  |  |

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