<SEC-DOCUMENT>0001213900-22-005856-index.html : 20220208
<SEC-HEADER>0001213900-22-005856.hdr.sgml : 20220208
<ACCEPTANCE-DATETIME>20220208124410
ACCESSION NUMBER:		0001213900-22-005856
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		26
FILED AS OF DATE:		20220208
DATE AS OF CHANGE:		20220208

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Blue Water Vaccines Inc.
		CENTRAL INDEX KEY:			0001782107
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-260137
		FILM NUMBER:		22600156

	BUSINESS ADDRESS:	
		STREET 1:		2041 COURTLAND AVENUE
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45212
		BUSINESS PHONE:		646-303-0737

	MAIL ADDRESS:	
		STREET 1:		2041 COURTLAND AVENUE
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45212
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>fs12022a6_bluewater.htm
<DESCRIPTION>REGISTRATION STATEMENT
<TEXT>
Document 1 - file: fs12022a6_bluewater.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.1
<SEQUENCE>2
<FILENAME>fs12022a6ex1-1_bluewater.htm
<DESCRIPTION>FORM OF UNDERWRITING AGREEMENT
<TEXT>
Document 2 - file: fs12022a6ex1-1_bluewater.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.2
<SEQUENCE>3
<FILENAME>fs12022a6ex4-2_bluewater.htm
<DESCRIPTION>FORM OF REPRESENTATIVE'S WARRANT*
<TEXT>
Document 3 - file: fs12022a6ex4-2_bluewater.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>4
<FILENAME>fs12022a6ex5-1_bluewater.htm
<DESCRIPTION>OPINION OF ELLENOFF GROSSMAN & SCHOLE LLP
<TEXT>
Document 4 - file: fs12022a6ex5-1_bluewater.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>5
<FILENAME>fs12022a6ex23-1_bluewater.htm
<DESCRIPTION>CONSENT OF MAYER HOFFMAN MCCANN P.C
<TEXT>
Document 5 - file: fs12022a6ex23-1_bluewater.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>6
<FILENAME>fs12022a6ex-fee_bluewater.htm
<DESCRIPTION>FILING FEE TABLE
<TEXT>
Document 6 - file: fs12022a6ex-fee_bluewater.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tblue_logo.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: tblue_logo.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>timage_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: timage_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>timage_002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: timage_002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>timage_003.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: timage_003.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>timage_004.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: timage_004.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>timage_005.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: timage_005.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>timage_006.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: timage_006.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>timage_007a.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: timage_007a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>timage_007b.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 15 - file: timage_007b.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>16
<FILENAME>timage_0013a.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 16 - file: timage_0013a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>17
<FILENAME>timage_008.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 17 - file: timage_008.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>timage_009.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 18 - file: timage_009.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>19
<FILENAME>timage_010.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 19 - file: timage_010.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>20
<FILENAME>timage_0101.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 20 - file: timage_0101.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>21
<FILENAME>timage_011.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 21 - file: timage_011.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>22
<FILENAME>ttable_003.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 22 - file: ttable_003.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>23
<FILENAME>timage_012.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 23 - file: timage_012.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>24
<FILENAME>ex5-1_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 24 - file: ex5-1_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>25
<FILENAME>ex23-1_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 25 - file: ex23-1_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>26
<FILENAME>ex23-1_002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 26 - file: ex23-1_002.jpg

</DOCUMENT>
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