    <SEC-DOCUMENT>0001213900-22-072414-index.html : 20221114
    <SEC-HEADER>0001213900-22-072414.hdr.sgml : 20221114
    <ACCEPTANCE-DATETIME>20221114171831
    ACCESSION NUMBER:		0001213900-22-072414
    CONFORMED SUBMISSION TYPE:	S-8
    PUBLIC DOCUMENT COUNT:		20
    REFERENCES 429:			333-265843
    FILED AS OF DATE:		20221114
    DATE AS OF CHANGE:		20221114
    EFFECTIVENESS DATE:		20221114

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Blue Water Vaccines Inc.
    		CENTRAL INDEX KEY:			0001782107
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-8
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-268357
    		FILM NUMBER:		221387729

    	BUSINESS ADDRESS:
    		STREET 1:		2041 COURTLAND AVENUE
    		CITY:			CINCINNATI
    		STATE:			OH
    		ZIP:			45212
    		BUSINESS PHONE:		646-303-0737

    	MAIL ADDRESS:
    		STREET 1:		2041 COURTLAND AVENUE
    		CITY:			CINCINNATI
    		STATE:			OH
    		ZIP:			45212
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>S-8
    <SEQUENCE>1
    <FILENAME>ea168413-s8_bluewater.htm
    <DESCRIPTION>REGISTRATION STATEMENT
    <TEXT>
    Document 1 - file: ea168413-s8_bluewater.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-5.1
    <SEQUENCE>2
    <FILENAME>ea168413ex5-1_bluewater.htm
    <DESCRIPTION>OPINION OF ELLENOFF GROSSMAN & SCHOLE LLP
    <TEXT>
    Document 2 - file: ea168413ex5-1_bluewater.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.1
    <SEQUENCE>3
    <FILENAME>ea168413ex23-1_bluewater.htm
    <DESCRIPTION>CONSENT OF MAYER HOFFMAN MCCANN P.C.
    <TEXT>
    Document 3 - file: ea168413ex23-1_bluewater.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-FILING FEES
    <SEQUENCE>4
    <FILENAME>ea168413ex-fee_bluewater.htm
    <DESCRIPTION>CALCULATION OF FILING FEE TABLES
    <TEXT>
    Document 4 - file: ea168413ex-fee_bluewater.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>image_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: image_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>image_022.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: image_022.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>image_003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: image_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>image_004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: image_004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>image_005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: image_005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>image_006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: image_006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>image_007.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: image_007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>image_008.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: image_008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>image_009.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: image_009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>image_010.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: image_010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>image_011.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: image_011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>image_012.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: image_012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>image_014.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: image_014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>image_015.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: image_015.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>image_016.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: image_016.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>ex5-1_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: ex5-1_001.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>