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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2013
Income Taxes [Abstract] |
Schedule of Deferred Tax Assets and Liabilities [Table Text Block] | Significant components of our deferred tax assets are as follows (in thousands):
|  | December 31, |
|  | 2013 |  | 2012 |
Deferred tax assets: |  |  |  |  |  |  |
Net operating loss carryforwards |  | $ | 85,912 |  | $ | 81,127 |
Research credit carryforwards |  |  | 13,481 |  |  | 12,750 |
Other, net |  |  | 3,962 |  |  | 4,190 |
Deferred revenue |  |  | 2,116 |  |  | 5,749 |
Total deferred tax assets |  |  | 105,471 |  |  | 103,816 |
Valuation allowance |  |  | (105,471) |  |  | (103,816) |
Net deferred tax assets |  | $ | — |  | $ | — |
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] | The effective tax rate of our provision (benefit) for income taxes differs from the federal statutory rate as follows (in thousands):
|  | Year Ending December 31, |
|  | 2013 |  | 2012 |  | 2011 |
Computed at 34% |  | $ | 3,301 |  | $ | (5,134) |  | $ | (5,168) |
State taxes |  |  | 213 |  |  | (234) |  |  | (228) |
Book gains (losses) not currently benefited |  |  | 1,656 |  |  | 3,120 |  |  | (1,264) |
Other |  |  | (476) |  |  | 1,901 |  |  | 2,746 |
Disallowed interest expense |  |  | 160 |  |  | 1,363 |  |  | 1,457 |
Income from debt restructuring |  |  | — |  |  | (1,615) |  |  | 2,462 |
Revaluation of warrant liability |  |  | (591) |  |  | 600 |  |  | — |
Research and development credits |  |  | (583) |  |  | — |  |  | — |
Non-cash gain from termination of royalty purchase agreement |  |  | (3,047) |  |  | — |  |  | — |
Non-cash gain on settlement of long-term debt |  |  | (632) |  |  | — |  |  | — |
Total |  | $ | 1 |  | $ | 1 |  | $ | 5 |

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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319 + Details
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