<SEC-DOCUMENT>0000950170-25-086548-index.html : 20250616
<SEC-HEADER>0000950170-25-086548.hdr.sgml : 20250616
<ACCEPTANCE-DATETIME>20250616081541
ACCESSION NUMBER:		0000950170-25-086548
CONFORMED SUBMISSION TYPE:	S-1
PUBLIC DOCUMENT COUNT:		13
FILED AS OF DATE:		20250616
DATE AS OF CHANGE:		20250616

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aptevo Therapeutics Inc.
		CENTRAL INDEX KEY:			0001671584
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				811567056
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-288061
		FILM NUMBER:		251048578

	BUSINESS ADDRESS:	
		STREET 1:		2401 4TH AVE.
		STREET 2:		SUITE 1050
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98121
		BUSINESS PHONE:		206-838-0500

	MAIL ADDRESS:	
		STREET 1:		2401 4TH AVE.
		STREET 2:		SUITE 1050
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98121
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1
<SEQUENCE>1
<FILENAME>apvo-2025-s1_-_june_offe.htm
<DESCRIPTION>S-1
<TEXT>
Document 1 - file: apvo-2025-s1_-_june_offe.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.20
<SEQUENCE>2
<FILENAME>apvo-ex4_20.htm
<DESCRIPTION>EX-4.20
<TEXT>
Document 2 - file: apvo-ex4_20.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.21
<SEQUENCE>3
<FILENAME>apvo-ex4_21.htm
<DESCRIPTION>EX-4.21
<TEXT>
Document 3 - file: apvo-ex4_21.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>4
<FILENAME>apvo-ex5_1.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 4 - file: apvo-ex5_1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.59
<SEQUENCE>5
<FILENAME>apvo-ex10_59.htm
<DESCRIPTION>EX-10.59
<TEXT>
Document 5 - file: apvo-ex10_59.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.60
<SEQUENCE>6
<FILENAME>apvo-ex10_60.htm
<DESCRIPTION>EX-10.60
<TEXT>
Document 6 - file: apvo-ex10_60.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>7
<FILENAME>apvo-ex23_1.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 7 - file: apvo-ex23_1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>8
<FILENAME>apvo-exfiling_fees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 8 - file: apvo-exfiling_fees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>img57496738_0.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: img57496738_0.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>img257065127_0.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: img257065127_0.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>img257065127_1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: img257065127_1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>img257065127_2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: img257065127_2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>img257065127_3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: img257065127_3.jpg

</DOCUMENT>
</SEC-DOCUMENT>