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Investments and Fair Value Instruments - Summary of Changes in Fair Value and Other Adjustments of Liabilities (Detail) - Level 3 [Member] $ in Thousands	9 Months Ended
	Sep. 30, 2022 USD ($)
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	$ 5,463
Initial recognition	4,015
Change in fair value and other adjustments	(1,950)
Ending Balance	4,135
Common Stock Warrant Liability [Member] | March 2018 Purchase Agreement [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	7
Initial recognition	0
Change in fair value and other adjustments	0
Ending Balance	0
Common Stock Warrant Liability [Member] | June 2019 Offering [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	170
Initial recognition	0
Change in fair value and other adjustments	0
Ending Balance	0
Common Stock Warrant Liability [Member] | September 2019 Offering [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	223
Initial recognition	0
Change in fair value and other adjustments	0
Ending Balance	0
Common Stock Warrant Liability [Member] | January 2021 Offering [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	2,993
Initial recognition	0
Change in fair value and other adjustments	0
Ending Balance	0
August 2022 Options [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	0
Initial recognition	3,824
Change in fair value and other adjustments	(1,791)
Ending Balance	2,033
August 2022 Placement Agent Options [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	0
Initial recognition	191
Change in fair value and other adjustments	(89)
Ending Balance	102
Contingent Liabilities [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Beginning Balance	2,070
Initial recognition	0
Change in fair value and other adjustments	(70)
Ending Balance	2,000
ASU 2020-06 [Member] | Reclassification upon Adoption [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	(3,392)
ASU 2020-06 [Member] | Reclassification upon Adoption [Member] | Common Stock Warrant Liability [Member] | March 2018 Purchase Agreement [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	(7)
ASU 2020-06 [Member] | Reclassification upon Adoption [Member] | Common Stock Warrant Liability [Member] | June 2019 Offering [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	(170)
ASU 2020-06 [Member] | Reclassification upon Adoption [Member] | Common Stock Warrant Liability [Member] | September 2019 Offering [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	(223)
ASU 2020-06 [Member] | Reclassification upon Adoption [Member] | Common Stock Warrant Liability [Member] | January 2021 Offering [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	(2,993)
ASU 2020-06 [Member] | Reclassification upon Adoption [Member] | August 2022 Options [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	0
ASU 2020-06 [Member] | Reclassification upon Adoption [Member] | August 2022 Placement Agent Options [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	0
ASU 2020-06 [Member] | Reclassification upon Adoption [Member] | Contingent Liabilities [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Ending Balance	$ 0

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