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Equity Financing - Additional Information (Detail) |  | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Aug. 16, 2022 USD ($) $ / shares | Aug. 31, 2022 USD ($) $ / shares shares | Jan. 31, 2021 USD ($) $ / shares shares | Dec. 31, 2020 USD ($) $ / shares shares | Sep. 30, 2019 USD ($) $ / shares shares | Jun. 30, 2019 USD ($) $ / shares shares | Jun. 30, 2018 USD ($) $ / shares shares | Mar. 31, 2018 USD ($) $ / shares shares | Dec. 31, 2022 USD ($) | Jun. 30, 2022 $ / shares | Jan. 28, 2021
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Stock price | $ / shares |  |  |  |  |  |  |  |  |  | $ 40.00 |
Maximum [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance, aggregate offering prices | $ |  |  |  |  |  |  |  |  | $ 50,000,000.0 |  |
March 2018 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  |  |  |  |  |  |  | 30,041 |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  |  |  |  | 32,071 |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  |  |  |  | $ 429.03 |  |  |
August 2022 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  | 61,250 |  |  |  |  |  |  |  |  |
Offering closing period |  | Aug. 16, 2022 |  |  |  |  |  |  |  |  |
August 2022 Purchase Agreement [Member] | Pre Funded Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  | 56,813 |  |  |  |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  | $ 0.004 |  |  |  |  |  |  |  |  |
August 2022 Purchase Agreement [Member] | Preferred Investment Options [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  | 118,063 |  |  |  |  |  |  |  |  |
Exercise price | $ / shares |  | $ 37.35 |  |  |  |  |  |  |  |  |
Proceeds from issuance of common stock, pre-funded warrants and preferred investment options | $ |  | $ 5,000,000.0 |  |  |  |  |  |  |  |  |
Warrants expiration period |  | 5 years |  |  |  |  |  |  |  |  |
December 2020 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  |  |  | 65,467 |  |  |  |  |  |  |
Proceeds from issuance of common stock and warrants gross | $ |  |  |  | $ 8,000,000.0 |  |  |  |  |  |  |
Offering closing period |  |  |  | Dec. 22, 2020 |  |  |  |  |  |  |
December 2020 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  | 65,467 |  |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  | $ 120.00 |  |  |  |  |  |  |
Warrants expiration period |  |  |  | 5 years 6 months |  |  |  |  |  |  |
September 2019 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  |  |  |  | 32,971 |  |  |  |  |  |
Proceeds from issuance of common stock and warrants gross | $ |  |  |  |  | $ 10,000,000.0 |  |  |  |  |  |
Offering closing period |  |  |  |  | Sep. 05, 2019 |  |  |  |  |  |
September 2019 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  | 16,486 |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  | $ 300.80 |  |  |  |  |  |
Warrants expiration period |  |  |  |  | 5 years 6 months |  |  |  |  |  |
June 2019 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  |  |  |  |  | 37,240 |  |  |  |  |
Proceeds from issuance of common stock and warrants gross | $ |  |  |  |  |  | $ 7,500,000 |  |  |  |  |
Offering closing period |  |  |  |  |  | Jun. 14, 2019 |  |  |  |  |
June 2019 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  |  | 37,240 |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  |  | $ 200.00 |  |  |  |  |
Warrants expiration period |  |  |  |  |  | 5 years 6 months |  |  |  |  |
June 2018 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  |  |  |  |  |  | 34,809 |  |  |  |
Proceeds from issuance of common stock and warrants gross | $ |  |  |  |  |  |  | $ 14,000,000.0 |  |  |  |
Offering closing period |  |  |  |  |  |  | Jun. 14, 2018 |  |  |  |
June 2018 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  |  |  | 34,809 |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  |  |  | $ 397.60 |  |  |  |
Warrants expiration period |  |  |  |  |  |  | 5 years 6 months |  |  |  |
June 2018 Placement Agent Warrants [Member] | June 2018 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  |  |  | 1,741 |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  |  |  | $ 502.72 |  |  |  |
Warrant, exercisable term |  |  |  |  |  |  | 5 years |  |  |  |
June 2019 Placement Agent Warrants [Member] | June 2019 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  |  | 1,862 |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  |  | $ 251.75 |  |  |  |  |
Warrant, exercisable term |  |  |  |  |  | 5 years |  |  |  |  |
September 2019 Placement Agent Warrants [Member] | September 2019 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  | 1,649 |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  | $ 379.12 |  |  |  |  |  |
Warrant, exercisable term |  |  |  |  | 5 years |  |  |  |  |  |
August 2022 Options and August 2022 Placement Agent Options [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expected volatility | 128.46% |  |  |  |  |  |  |  |  |  |
Stock price | $ / shares | $ 37.60 |  |  |  |  |  |  |  |  |  |
Risk-free interest rate | 2.97% |  |  |  |  |  |  |  |  |  |
Expected term | 5 years |  |  |  |  |  |  |  |  |  |
August 2022 Placement Agent Options [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Fair value assumptions, value | $ | $ 191,000 |  |  |  |  |  |  |  |  |  |
Offering costs | $ | 488,000 |  |  |  |  |  |  |  |  |  |
Allocation of common stock option liability expense | $ | 314,000 |  |  |  |  |  |  |  |  |  |
Remaining offering costs allocated to common stock and offset to additional paid in capital | $ | 365,000 |  |  |  |  |  |  |  |  |  |
August 2022 Placement Agent Options [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering costs | $ | $ 679,000 |  |  |  |  |  |  |  |  |  |
August 2022 Placement Agent Options [Member] | August 2022 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  | 5,904 |  |  |  |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  | $ 52.80 |  |  |  |  |  |  |  |  |
Warrant, exercisable term |  | 5 years |  |  |  |  |  |  |  |  |
December 2020 Placement Agent Warrants [Member] | December 2020 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  | 3,274 |  |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  |  | $ 152.75 |  |  |  |  |  |  |
Warrant, exercisable term |  |  |  | 5 years |  |  |  |  |  |  |
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  |  | 196,920 |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  | 98,460 |  |  |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  | $ 125.20 |  |  |  |  |  |  |  |
Proceeds from issuance of common stock and warrants gross | $ |  |  | $ 25,100,000 |  |  |  |  |  |  |  |
Warrants expiration period |  |  | 5 years 6 months |  |  |  |  |  |  |  |
Remaining offering costs allocated to common stock and offset to additional paid in capital | $ |  |  | $ 2,000,000.0 |  |  |  |  |  |  |  |
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering costs allocated to common stock warrant liability and expensed | $ |  |  | $ 769,000 |  |  |  |  |  |  |  |
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] | Expected Volatility [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Preferred investment options liability, measurement input |  |  |  |  |  |  |  |  |  |  | 1.238
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] | Stock Price [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Preferred investment options liability, measurement input |  |  |  |  |  |  |  |  |  |  | 1.1520
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] | Risk-Free Interest Rate [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Preferred investment options liability, measurement input |  |  |  |  |  |  |  |  |  |  | 0.05
January 2021 Private Placement [Member] | January 2021 Placement Agent Warrants [Member] | January 2021 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  | 9,846 |  |  |  |  |  |  |  |
Warrants issued, exercise price | $ / shares |  |  | $ 159.60 |  |  |  |  |  |  |  |
Offering costs | $ |  |  | $ 1,900,000 |  |  |  |  |  |  |  |
Warrant, exercisable term |  |  | 5 years 6 months |  |  |  |  |  |  |  |
Issuance of placement agent warrants | $ |  |  | $ 942,000 |  |  |  |  |  |  |  |
January 2021 Private Placement [Member] | January 2021 Placement Agent Warrants [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Offering costs | $ |  |  | $ 2,800,000 |  |  |  |  |  |  |  |
March 2018 Private Placement [Member] | March 2018 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares of common stock issued |  |  |  |  |  |  |  | 7,519 |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  |  |  |  | 7,519 |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  |  |  |  | $ 1,830.00 |  |  |
Proceeds from issuance of common stock and warrants gross | $ |  |  |  |  |  |  |  | $ 10,000,000.0 |  |  |
Warrants expiration period |  |  |  |  |  |  |  | 5 years |  |  |
March 2018 Private Placement [Member] | March 2018 Placement Agent Warrants [Member] | March 2018 Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Class Of Warrant Or Right [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant issued, shares of common stock called by warrant |  |  |  |  |  |  |  | 376 |  |  |
Warrants issued, exercise price | $ / shares |  |  |  |  |  |  |  | $ 1,662.50 |  |  |
Warrant, exercisable term |  |  |  |  |  |  |  | 5 years |  |  |

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- Definition Amount of decrease in additional paid in capital (APIC) resulting from direct costs associated with issuing stock. Includes, but is not limited to, legal and accounting fees and direct costs associated with stock issues under a shelf registration. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 2 -URI https://asc.fasb.org/extlink&oid=126973232&loc=d3e21463-112644 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.3-04) -URI https://asc.fasb.org/extlink&oid=120397183&loc=d3e187085-122770 + Details
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- Definition The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(ii) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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