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Warrants and Options - Summary of Warrants Issued to Purchase Common Stock (Detail) - $ / shares | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2023 | Dec. 31, 2022
Class Of Warrant Or Right [Line Items] |  |
Exercised during the period | 56,813 | 0
Outstanding | 769,532 | 342,570
March 2023 Pre-Funded Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2023-03 |
Term | perpetual |
Exercise Price Per Share | $ 0 |
Exercised during the period | 0 | 0
Outstanding | 500,834 | 0
December 2022 Service and Performance Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2022-12 |
Term | 5 years |
Exercise Price Per Share | $ 11.20 |
Exercised during the period | 0 | 0
Outstanding | 1,000 | 1,000
October 2022 Service and Performance Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2022-10 |
Term | 5 years |
Exercise Price Per Share | $ 16.00 |
Exercised during the period | 0 | 0
Outstanding | 1,000 | 1,000
August 2022 Pre-Funded Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2022-08 |
Term | perpetual |
Exercise Price Per Share | $ 0 |
Exercised during the period | (56,813) | 0
Outstanding | 0 | 56,813
January 2021 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2021-01 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 159.60 |
Exercised during the period | 0 | 0
Outstanding | 9,846 | 9,846
January 2021 Service and Performance Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2021-01 |
Term | 2 years |
Exercise Price Per Share | $ 123.20 |
Exercised during the period | 0 | 0
Outstanding | 0 | 188
December 2020 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-12 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 9.00 |
Exercised during the period | 0 | 0
Outstanding | 16,367 | 16,367
December 2020 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-12 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 120.00 |
Exercised during the period | 0 | 0
Outstanding | 49,100 | 49,100
December 2020 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-12 |
Term | 5 years |
Exercise Price Per Share | $ 152.80 |
Exercised during the period | 0 | 0
Outstanding | 3,274 | 3,274
July 2020 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-07 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 9.00 |
Exercised during the period | 0 | 0
Outstanding | 16,036 | 16,036
July 2020 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-07 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 198.80 |
Exercised during the period | 0 | 0
Outstanding | 802 | 802
May 2020 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-05 |
Term | 5 years |
Exercise Price Per Share | $ 9.00 |
Exercised during the period | 0 | 0
Outstanding | 9,946 | 9,946
May 2020 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-05 |
Term | 5 years |
Exercise Price Per Share | $ 191.20 |
Exercised during the period | 0 | 0
Outstanding | 24,863 | 24,863
May 2020 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-05 |
Term | 5 years |
Exercise Price Per Share | $ 245.20 |
Exercised during the period | 0 | 0
Outstanding | 1,741 | 1,741
March 2020 Service and Performance Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2020-03 |
Term | 3 years |
Exercise Price Per Share | $ 100.00 |
Exercised during the period | 0 | 0
Outstanding | 0 | 459
September 2019 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2019-09 |
Term | 5 years |
Exercise Price Per Share | $ 379.20 |
Exercised during the period | 0 | 0
Outstanding | 1,649 | 1,649
June 2019 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2019-06 |
Term | 5 years |
Exercise Price Per Share | $ 251.60 |
Exercised during the period | 0 | 0
Outstanding | 1,862 | 1,862
April 2019 Service and Performance Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2019-04 |
Term | 5 years |
Exercise Price Per Share | $ 247.20 |
Exercised during the period | 0 | 0
Outstanding | 3,629 | 3,629
June 2018 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2018-06 |
Term | 5 years |
Exercise Price Per Share | $ 502.80 |
Exercised during the period | 0 | 0
Outstanding | 1,741 | 1,741
March 2018 Placement Agent Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2018-03 |
Term | 5 years |
Exercise Price Per Share | $ 1,662.40 |
Exercised during the period | 0 | 0
Outstanding | 0 | 376
January 2021 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2021-01 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 9.00 |
Exercised during the period | 0 | 0
Outstanding | 7,831 | 7,831
January 2021 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2021-01 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 125.20 |
Exercised during the period | 0 | 0
Outstanding | 90,629 | 90,629
September 2019 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2019-09 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 9.00 |
Exercised during the period | 0 | 0
Outstanding | 9,892 | 9,892
September 2019 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2019-09 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 300.80 |
Exercised during the period | 0 | 0
Outstanding | 6,594 | 6,594
June 2019 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2019-06 |
Term | 5 years 6 months |
Exercise Price Per Share | $ 200.00 |
Exercised during the period | 0 | 0
Outstanding | 10,896 | 10,896
March 2018 Warrants [Member] |  |
Class Of Warrant Or Right [Line Items] |  |
Issuance Date | 2018-03 |
Term | 5 years |
Exercise Price Per Share | $ 429.20 |
Exercised during the period | 0 | 0
Outstanding | 0 | 16,036

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