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Stock-Based Compensation and Employee Stock Purchase Program | 6 Months Ended
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Jun. 30, 2023
Share-Based Payment Arrangement [Abstract] |
Stock-Based Compensation and Employee Stock Purchase Program | 11. Stock-Based Compensation and Employee Stock Purchase Program Stock Incentive Plans The Company has two equity incentive plans: the 2006 Stock Plan (“2006 Plan”) and the 2015 Omnibus Equity Incentive Plan (“2015 Plan”). In 2006, the Company adopted the 2006 Plan, which provided for the granting of stock options to executives, employees, and other service providers under terms and provisions established by the Board of Directors. The Company granted non-statutory stock options (“NSOs”) under the 2006 Plan until May 2015, when it was terminated as to future awards, although it continues to govern the terms of options that remain outstanding and were issued under the 2006 Plan. The 2015 Plan became effective upon the Company’s IPO in May 2015 and all shares that were reserved, but not issued, under the 2006 Plan were assumed by the 2015 Plan. Upon effectiveness, the 2015 Plan had 3,860 shares of common stock reserved for future issuance, which included 259 that were transferred to and assumed by the 2015 Plan. The 2015 Plan provides for automatic annual increases in shares available for grant. In addition, shares subject to awards under the 2006 Plan that are forfeited or canceled will be added to the 2015 Plan. The 2015 Plan provides for the grant of incentive stock options (“ISOs”), NSOs, restricted stock awards, stock units, stock appreciation rights, and other forms of equity compensation, all of which may be granted to employees, officers, non-employee directors, and consultants. The exercise price for ISOs and NSOs will be granted at a price per share not less than the fair value of our common stock at the date of grant. Options granted generally vest over a four-year period; however, there might be alternative vesting schedules, as approved by the Board. Options granted, once vested, are generally exercisable for up to 10 years, after grant to the extent vested. In June 2019, the shareholders approved an amendment to the Company’s 2015 Plan for a one-time increase to the number of shares of common stock that may be issued under the 2015 Plan by 3,000 shares. On February 2, 2022, Sta nley Jacot, Jr. was hired as the new president and chief executive officer of the Company. The Company granted Mr. Jacot an inducement stock option to purchase 7,902 shares of the Company’s common stock pursuant to Rule 5635(c)(4) of the Nasdaq Listing Rules. The Company has filed a registration statement on Form S-8 to register the issuance of shares upon exercise of this inducement stock option. The inducement options grants have been issued outside of the 2015 Plan, but are subject to the terms and conditions of the 2015 Plan. As of June 30, 2023, a total of 86,834 shares of common stock were reserved for issuance under the 2015 Plan, of which 10,660 shares of common stock are available for future grant. As of June 30, 2023, a total of 103 and 76,174 options are outstanding under the 2006 and 2015 Plans, respectively. As of December 31, 2022, a total of 103 and 51,421 options were outstanding under the 2006 and 2015 Plans, respectively. A total of 8,477 inducement options were outstanding as of June 30, 2023 and December 31, 2022. The following is a summary of stock option information and weighted average exercise prices under the Company’s stock incentive plans (in thousands, except share data and price per share):
|  | Shares Subject to Outstanding Options |  |  | Weighted- Average Exercise Price Per Share |  |  | Aggregate Intrinsic Value |
Outstanding — Balance at December 31, 2022 |  |  | 60,002 |  |  | $ | 114.80 |  |  | $ | — |
Options granted |  |  | 26,021 |  |  |  | 6.38 |  |  |  | — |
Options exercised |  |  | — |  |  |  | — |  |  |  | — |
Options forfeited |  |  | (1,058 | ) |  |  | 39.05 |  |  |  | 39,062 |
Options expired |  |  | (210 | ) |  |  | 118.35 |  |  |  | — |
Outstanding — Balance at June 30, 2023 |  |  | 84,755 |  |  | $ | 82.21 |  |  | $ | — |
Vested and expected to vest — June 30, 2023 |  |  | 76,998 |  |  | $ | 87.98 |  |  | $ | — |
Exercisable — June 30, 2023 |  |  | 35,364 |  |  | $ | 155.85 |  |  | $ | — |
Aggregate intrinsic value represents the difference between the exercise price of the options and the estimated fair value of the Company’s common stock determined by its Board of Directors for each of the respective periods. As of June 30, 2023, there was $969,000 of unrecognized compensation cost related to unvested stock-based compensation grants that will be recognized over the weighted-average remaining recognition period of 2.2 years. In determining the fair value of the stock-based awards, the Company uses the Black-Scholes option-pricing model and assumptions discussed below. Each of these inputs is subjective and generally requires significant judgment to determine. Expected Term—The expected term is the estimated period of time outstanding for stock options granted and was estimated based on a simplified method allowed by the SEC, and defines the term as the average of the contractual term of the options and the weighted-average vesting period for all open employee awards. Expected Volatility—The historical volatility data was computed using the daily closing prices for the Company’s shares during the equivalent period of the calculated expected term of the stock-based awards. Risk-Free Interest Rate—The risk-free interest rate is based on the interest rate of U.S. Treasuries of comparable maturities on the date the options were granted. Expected Dividend—The expected dividend yield is based on the Company’s expectation of future dividend payouts to common stockholders. The fair value of stock option awards was estimated at the date of grant using the Black-Scholes option-pricing model with the following weighted-average assumption:
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2023 |  |  | 2022 |  |  | 2023 |  |  | 2022 |
Expected term (years) |  |  | 7.20 |  |  |  | 6.85 |  |  |  | 7.06 |  |  |  | 6.61 |
Expected volatility |  |  | 124 | % |  |  | 123 | % |  |  | 124 | % |  |  | 122 | %
Risk-free interest rate |  |  | 3.59 | % |  |  | 2.85 | % |  |  | 3.61 | % |  |  | 2.48 | %
Dividend yield |  |  | — |  |  |  | — |  |  |  | — |  |  |  | — |
The Company recognized $199,000 and $411,000 of compensation expense for stock options awards during the three and six months ended June 30, 2023, respectively. The Company recognized $323,000 and $583,000 of compensation expense for stock options awards for the three and six months ended June 30, 2022, respectively. Employee Stock Purchase Plan The Company’s 2015 Employee Stock Purchase Plan (“ESPP”) became effective on May 14, 2015. The ESPP allows eligible employees to purchase shares of the Company’s common stock at a discount of up to 15% of their eligible compensation through payroll deductions, subject to any plan limitations. After the first offering period, which began on May 14, 2015 and ended on February 1, 2016, the ESPP provides for six-month offering periods, and at the end of each offering period, employees are able to purchase shares at 85% of the lower of the fair market value of the Company’s common stock on the first trading day of the offering period or on the last day of the offering period. As of June 30, 2023, the number of shares of common stock reserved for future issuance under the ESPP is 9,170. The ESPP provides for automatic annual increases in the shares available for purchase beginning on January 1, 2016. As of June 30, 2023, 1,563 shares had been issued under the ESPP. The Company recorded $2,000 and $3,000 of ESPP related compensation expense during the three and six months ended June 30, 2023, respectively. The Company recorded $1,000 and $2,000 of ESPP related compensation expense for the three and six months ended June 30, 2022, respectively.

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