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Stock-Based Compensation and Employee Stock Purchase Program - Summary of Activity Under Stock Incentive Plans (Detail)
$ / shares in Units, $ in Thousands
 6 Months Ended
Jun. 30, 2024
USD ($)
$ / shares
shares
Share-Based Payment Arrangement [Abstract]  
Shares Subject to Outstanding, Beginning Balance | shares 80,078
Shares Subject to Outstanding, Options Forfeited | shares (3,425)
Shares Subject to Outstanding, Options Expired | shares (12,479)
Shares Subject to Outstanding, Ending Balance | shares 64,174
Shares Subject to Outstanding, Vested and expected to vest | shares 72,526
Shares Subject to Outstanding, Exercisable | shares 42,084
Weighted-Average Exercise Price Per Share, Outstanding Beginning Balance | $ / shares $ 85.30
Weighted-Average Exercise Price Per Share, Options forfeited | $ / shares 21.71
Weighted-Average Exercise Price Per Share, Options expired | $ / shares 164.76
Weighted Average Exercise Price Per Share, Outstanding Ending Balance | $ / shares 73.23
Weighted Average Exercise Price Per Share, Vested and expected to vest | $ / shares 75.84
Weighted Average Exercise Price Per Share, Exercisable | $ / shares $ 91.7
Aggregate Intrinsic Value, Beginning Balance | $ $ 0
Aggregate Intrinsic Value, Options Forfeited | $ 0
Aggregate Intrinsic Value, Options Expired | $ 0
Aggregate Intrinsic Value, Ending Balance | $ 0
Aggregate Intrinsic Value, Vested and expected to vest | $ 0
Aggregate Intrinsic Value, Exercisable | $ $ 0