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Stock-Based Compensation and Employee Stock Purchase Program - Summary of Activity Under Stock Incentive Plans (Detail)
$ / shares in Units, $ in Thousands
 9 Months Ended
Sep. 30, 2024
USD ($)
$ / shares
shares
Share-Based Payment Arrangement [Abstract]  
Shares Subject to Outstanding, Beginning Balance | shares 80,078
Shares Subject to Outstanding, Options Granted | shares 158,000
Shares Subject to Outstanding, Options Forfeited | shares (7,927)
Shares Subject to Outstanding, Options Expired | shares (12,576)
Shares Subject to Outstanding, Ending Balance | shares 217,575
Shares Subject to Outstanding, Vested and expected to vest | shares 198,542
Shares Subject to Outstanding, Exercisable | shares 50,515
Weighted-Average Exercise Price Per Share, Outstanding Beginning Balance | $ / shares $ 85.30
Weighted-Average Exercise Price Per Share, Options granted | $ / shares 2.71
Weighted-Average Exercise Price Per Share, Options forfeited | $ / shares 19.08
Weighted-Average Exercise Price Per Share, Options expired | $ / shares 170.08
Weighted Average Exercise Price Per Share, Outstanding Ending Balance | $ / shares 22.83
Weighted Average Exercise Price Per Share, Vested and expected to vest | $ / shares 24.68
Weighted Average Exercise Price Per Share, Exercisable | $ / shares $ 84.37
Aggregate Intrinsic Value, Beginning Balance | $ $ 0
Aggregate Intrinsic Value, Options Granted | $ 0
Aggregate Intrinsic Value, Options Forfeited | $ 397
Aggregate Intrinsic Value, Options Expired | $ 0
Aggregate Intrinsic Value, Ending Balance | $ 3,140
Aggregate Intrinsic Value, Vested and expected to vest | $ 2,778
Aggregate Intrinsic Value, Exercisable | $ $ 0