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Stock-Based Compensation and Employee Stock Purchase Program (Tables)

9 Months Ended

12 Months Ended

Sep. 30, 2024

Dec. 31, 2023

Share-Based Payment Arrangement [Abstract]

Summary of Activity Under Stock Incentive Plans

The following is a summary of stock option information and weighted average exercise prices under the Company’s stock incentive plans (in thousands, except share data and price per share):

		Shares Subject to Outstanding Options				Weighted- Average Exercise Price Per Share				Aggregate Intrinsic Value
Outstanding — Balance at December 31, 2023			80,078			$	85.30			$	—
Options granted			158,000				2.71				—
Options forfeited			(7,927	)			19.08			$	397
Options expired			(12,576	)			170.08				—
Outstanding — Balance at September 30, 2024			217,575			$	22.83			$	3,140
Vested and expected to vest — September 30, 2024			198,542			$	24.68			$	2,778
Exercisable — September 30, 2024			50,515			$	84.37			$	—

The following is a summary of stock option information and weighted average exercise prices under the Company’s stock incentive plans (in thousands, except share data and price per share):

		Shares Subject to Outstanding Options				Weighted- Average Exercise Price Per Share				Aggregate Intrinsic Value
Outstanding — Balance at December 31, 2021			35,554			$	211.20			$	—
Options granted			33,408				44.00				11,880
Options exercised			—				—				—
Options forfeited			(6,658	)			91.60				—
Options expired			(2,302	)			644.80				—
Outstanding — Balance at December 31, 2022			60,002				114.80				—
Options granted			26,021				6.38				—
Options exercised			—				—				—
Options forfeited			(5,644	)			29.58				39,062
Options expired			(301	)			121.05				—
Outstanding — Balance at December 31, 2023			80,078				85.30				—
Vested and expected to vest — December 31, 2023			74,608				89.85				—
Exercisable —December 31, 2023			41,735			$	139.82			$	—

Weighted-Average Fair Value Assumption of Stock Option Awards

The fair value of stock option awards was estimated at the date of grant using the Black-Scholes option-pricing model with the following weighted-average assumption:

		Year Ended December 31,
Assumptions		2023				2022
Expected term (years)			7.06				6.40
Expected volatility			124	%			122	%
Risk-free interest rate			3.61	%			2.61	%
Expected dividend yield			—				—

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- Definition

Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 718
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (c)(1)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480429/718-10-50-2

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-Name Accounting Standards Codification
-Section 50
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-URI https://asc.fasb.org/1943274/2147480429/718-10-50-2

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-Name Accounting Standards Codification
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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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-Subparagraph (f)(2)
-Name Accounting Standards Codification
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