    <SEC-DOCUMENT>0001683168-24-007520-index.html : 20241031
    <SEC-HEADER>0001683168-24-007520.hdr.sgml : 20241031
    <ACCEPTANCE-DATETIME>20241031165029
    ACCESSION NUMBER:		0001683168-24-007520
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20231231
    FILED AS OF DATE:		20241031
    DATE AS OF CHANGE:		20241031
    EFFECTIVENESS DATE:		20241031

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Xenetic Biosciences, Inc.
    		CENTRAL INDEX KEY:			0001534525
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				452952962
    		STATE OF INCORPORATION:			NV
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37937
    		FILM NUMBER:		241415884

    	BUSINESS ADDRESS:
    		STREET 1:		945 CONCORD ST.
    		CITY:			FRAMINGHAM
    		STATE:			MA
    		ZIP:			01701
    		BUSINESS PHONE:		781-778-7720

    	MAIL ADDRESS:
    		STREET 1:		945 CONCORD ST.
    		CITY:			FRAMINGHAM
    		STATE:			MA
    		ZIP:			01701

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	General Sales & Leasing, Inc.
    		DATE OF NAME CHANGE:	20130227

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	GENERAL AIRCRAFT INC.
    		DATE OF NAME CHANGE:	20111108
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>xenetic_ars1.pdf
    <DESCRIPTION>ANNUAL REPORT TO SECURITY HOLDERS
    <TEXT>
    Document 1 - file: xenetic_ars1.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>