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STOCK BASED COMPENSATION - Stock based compensation expense (Details) - USD ($) | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024
STOCK BASED COMPENSATION |  |  |  |
Share-Based Payment Arrangement, Grantee Status [Extensible Enumeration] |  |  | us-gaap:ShareBasedPaymentArrangementNonemployeeMember |
Intrinsic value of exercisable options | $ 0 |  | $ 0 |
Stock-based compensation expense | 321,000 | $ 313,000 | 682,000 | $ 619,000
Unrecognized stock compensation expense | 3,100,000 |  | $ 3,100,000 |
Unrecognized stock compensation expense expected to be recognized over the remaining weighted average service period |  |  | 3 years 4 months 6 days |
ADSs | Amended plan |  |  |  |
STOCK BASED COMPENSATION |  |  |  |
Grants subject to shareholder approval |  |  | 31,469 |
Granted |  |  | 124,514 | 0
Research and Development Expense |  |  |  |
STOCK BASED COMPENSATION |  |  |  |
Stock-based compensation expense | 86,000 | 68,000 | $ 206,000 | $ 118,000
General and Administrative Expense |  |  |  |
STOCK BASED COMPENSATION |  |  |  |
Stock-based compensation expense | $ 235,000 | $ 245,000 | $ 476,000 | $ 501,000

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