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STOCK BASED COMPENSATION - Stock based compensation expense (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
STOCK BASED COMPENSATION
Share-Based Payment Arrangement, Grantee Status [Extensible Enumeration]			us-gaap:ShareBasedPaymentArrangementNonemployeeMember
Intrinsic value of exercisable options	$ 0		$ 0
Stock-based compensation expense	321,000	$ 313,000	682,000	$ 619,000
Unrecognized stock compensation expense	3,100,000		$ 3,100,000
Unrecognized stock compensation expense expected to be recognized over the remaining weighted average service period			3 years 4 months 6 days
ADSs | Amended plan
STOCK BASED COMPENSATION
Grants subject to shareholder approval			31,469
Granted			124,514	0
Research and Development Expense
STOCK BASED COMPENSATION
Stock-based compensation expense	86,000	68,000	$ 206,000	$ 118,000
General and Administrative Expense
STOCK BASED COMPENSATION
Stock-based compensation expense	$ 235,000	$ 245,000	$ 476,000	$ 501,000

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