<SEC-DOCUMENT>0001104659-25-059529.txt : 20250613
<SEC-HEADER>0001104659-25-059529.hdr.sgml : 20250613
<ACCEPTANCE-DATETIME>20250613200637
ACCESSION NUMBER:		0001104659-25-059529
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20250529
FILED AS OF DATE:		20250613
DATE AS OF CHANGE:		20250613

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Myers Michael
		CENTRAL INDEX KEY:			0001959547
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37846
		FILM NUMBER:		251048195

	MAIL ADDRESS:	
		STREET 1:		AZRIELI CENTER
		STREET 2:		ROUND TOWER, 30TH FLOOR
		CITY:			TEL AVIV
		STATE:			L3
		ZIP:			6701101

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Quoin Pharmaceuticals, Ltd.
		CENTRAL INDEX KEY:			0001671502
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			L3

	BUSINESS ADDRESS:	
		STREET 1:		23 HATA'AS STREET
		CITY:			KFAR SABA
		STATE:			L3
		ZIP:			44425
		BUSINESS PHONE:		97299741444

	MAIL ADDRESS:	
		STREET 1:		23 HATA'AS STREET
		CITY:			KFAR SABA
		STATE:			L3
		ZIP:			44425

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cellect Biotechnology Ltd.
		DATE OF NAME CHANGE:	20160721

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cellect Biomed Ltd.
		DATE OF NAME CHANGE:	20160406
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>tm2518028-4_4aseq1.xml
<DESCRIPTION>OWNERSHIP DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0508</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2025-05-29</periodOfReport>

    <dateOfOriginalSubmission>2025-06-02</dateOfOriginalSubmission>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001671502</issuerCik>
        <issuerName>Quoin Pharmaceuticals, Ltd.</issuerName>
        <issuerTradingSymbol>QNRX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001959547</rptOwnerCik>
            <rptOwnerName>Myers Michael</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O QUOIN PHARMACEUTICALS LTD.,</rptOwnerStreet1>
            <rptOwnerStreet2>42127 PLEASANT FOREST COURT</rptOwnerStreet2>
            <rptOwnerCity>ASHBURN</rptOwnerCity>
            <rptOwnerState>VA</rptOwnerState>
            <rptOwnerZipCode>20148</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Executive Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>0</aff10b5One>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Share Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>9.07</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2025-05-29</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness></transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>42857</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2035-05-29</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>ADS</value>
                    <footnoteId id="F1"/>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>42857</value>
                    <footnoteId id="F1"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>42857</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The number of securities underlying the option and the exercise price are listed in terms of American Depositary Shares (&quot;ADSs&quot;). Each ADS represents thirty-five ordinary shares of the Issuer. On June 2, 2025, the reporting person filed a Form 4 which inadvertently understated the number of ADSs underlying the option granted to the reporting person on May 29, 2025.</footnote>
        <footnote id="F2">The option vests in four annual installments with 20% vesting on each of May 29, 2026, 2027 and 2028 and 40% vesting on May 29, 2029.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Michael Myers</signatureName>
        <signatureDate>2025-06-13</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
