<SEC-DOCUMENT>0001641172-25-016626.txt : 20250626
<SEC-HEADER>0001641172-25-016626.hdr.sgml : 20250626
<ACCEPTANCE-DATETIME>20250626145337
ACCESSION NUMBER:		0001641172-25-016626
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		<ITEMS>06b
FILED AS OF DATE:		20250626
DATE AS OF CHANGE:		20250626
EFFECTIVENESS DATE:		20250626

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Shuttle Pharmaceuticals Holdings, Inc.
		CENTRAL INDEX KEY:			0001757499
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-550014
		FILM NUMBER:		251079091

	BUSINESS ADDRESS:	
		STREET 1:		401 PROFESSIONAL DRIVE
		STREET 2:		SUITE 260
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20879
		BUSINESS PHONE:		(240) 403-4212

	MAIL ADDRESS:	
		STREET 1:		401 PROFESSIONAL DRIVE
		STREET 2:		SUITE 260
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20879
</SEC-HEADER>
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        <cik>0001757499</cik>
        <entityName>Shuttle Pharmaceuticals Holdings, Inc.</entityName>
        <issuerAddress>
            <street1>401 PROFESSIONAL DRIVE, SUITE 260</street1>
            <city>GAITHERSBURG</city>
            <stateOrCountry>MD</stateOrCountry>
            <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
            <zipCode>20879</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>240-403-4212</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>Shuttle Pharma Acquisition Corp., Inc.</previousName>
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        <edgarPreviousNameList>
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        <entityType>Corporation</entityType>
        <yearOfInc>
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    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <lastName>Cooper</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Shuttle Pharmaceuticals</street1>
                <street2>401 Professional Drive, suite 260</street2>
                <city>Gaithersburg</city>
                <stateOrCountry>MD</stateOrCountry>
                <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
                <zipCode>20879</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chief Executive Officer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Peter</firstName>
                <lastName>Dritschilo</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Shuttle Pharmaceuticals</street1>
                <street2>401 Professional Drive, Suite 260</street2>
                <city>Gaithersburg</city>
                <stateOrCountry>MD</stateOrCountry>
                <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
                <zipCode>208579</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>President and Chief Operating Officer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mira</firstName>
                <lastName>Jung</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Shuttle Pharmaceuticals</street1>
                <street2>401 Professional Drive, Suite 260</street2>
                <city>Gaithersburg</city>
                <stateOrCountry>MD</stateOrCountry>
                <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
                <zipCode>20879</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chief Scientific Officer for Biology</relationshipClarification>
        </relatedPersonInfo>
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                <firstName>Tyvin</firstName>
                <lastName>Rich</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
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                <street2>401 Professional Drive, Suite 260</street2>
                <city>Gaithersburg</city>
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                <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
                <zipCode>20879</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
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            </relatedPersonRelationshipList>
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        </relatedPersonInfo>
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                <firstName>Timothy</firstName>
                <lastName>Lorber</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Shuttle Pharmaceuticals</street1>
                <street2>401 Professional Drive, Suite 260</street2>
                <city>Gaithersburg</city>
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                <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
                <zipCode>20879</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>Chief Financial Officer</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>George</firstName>
                <lastName>Scorcis</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Shuttle Pharmaceuticals</street1>
                <street2>401 Professional Drive, Suite 260</street2>
                <city>Gaithersburg</city>
                <stateOrCountry>MD</stateOrCountry>
                <stateOrCountryDescription>MARYLAND</stateOrCountryDescription>
                <zipCode>20879</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steven</firstName>
                <lastName>Richards</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
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                <zipCode>20879</zipCode>
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            </relatedPersonAddress>
            <relatedPersonRelationshipList>
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    <offeringData>
        <industryGroup>
            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06b</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2025-06-20</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>WestPark Capital, Inc.</recipientName>
                <recipientCRDNumber>000039914</recipientCRDNumber>
                <associatedBDName>WestPark Capital, Inc.</associatedBDName>
                <associatedBDCRDNumber>000039914</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>535 5th Avenue, 22nd Floor</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10017</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>DE</state>
                    <description>DELAWARE</description>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>4250000</totalOfferingAmount>
            <totalAmountSold>4250000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>170000</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Shuttle Pharmaceuticals Holdings, Inc.</issuerName>
                <signatureName>/s/ Christopher Cooper</signatureName>
                <nameOfSigner>Christopher Cooper</nameOfSigner>
                <signatureTitle>Interim Chief Executive Officer</signatureTitle>
                <signatureDate>2025-06-25</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
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