Exhibit 32.1

Certification of Principal Executive Officer Pursuant to 18 U.S.C. Section 1350 as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, I, Rajiv De Silva, the Chief Executive Officer of Venus Concept Inc. (the “Company”), hereby certify, that, to my knowledge:

1. | The Annual Report on Form 10-K for the year ended 2022 (the “Report”) of the Company fully complies with the requirements of Section 13(a) of the Securities Exchange Act of 1934; and

2. | The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

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Date: March 27, 2023 | By: | /s/ Rajiv De Silva
|  | Name: Rajiv De Silva Chief Executive Officer (Principal Executive Officer)