December 31, 2022

December 31, 2021

Outstanding common stock warrants

15,928,867

Outstanding stock options and RSUs

13,130,144

5,977,179

Preferred shares

31,850,000

3,790,755

Shares reserved for conversion of future non-voting preferred share issuance

1,209,245

Shares reserved for conversion of future voting preferred share issuance

9,150,000

—

Shares reserved for future option grants and RSUs

376,201

589,064

Shares reserved for Lincoln Park

15,814,471

5,222,867

Shares reserved for Madryn Noteholders

8,215,706

8,213,880

Total common stock reserved for issuance

95,674,634

40,931,857