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Stock-Based Compensation (Details Textual) (USD $)
 0 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended 0 Months Ended 12 Months Ended
Apr. 06, 2011
Jul. 28, 2011
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2001
2001 Stock Plan [Member]
Dec. 31, 2012
2001 Stock Plan [Member]
Dec. 31, 2012
Subsequent Event [Member]
Oct. 25, 2012
Warrant [Member]
Mar. 15, 2012
Warrant [Member]
Feb. 02, 2012
Warrant [Member]
Dec. 31, 2012
Warrant [Member]
Jul. 28, 2011
Warrant [Member]
Apr. 06, 2011
Warrant [Member]
Dec. 31, 2012
Warrant [Member]
General And Administrative Expenses And Research And Development Expense [Member]
Dec. 31, 2012
Epitope [Member]
Apr. 06, 2011
Common Stock Purchase Agreement With Single Investors [Member]
Jan. 28, 2011
Common Stock Purchase Agreement With Single Investors [Member]
Jul. 02, 2010
Common Stock Purchase Agreement With Single Investors [Member]
Apr. 06, 2011
Stock Purchase Agreement With Three Institutional Investors [Member]
Jan. 28, 2011
Stock Purchase Agreement With Three Institutional Investors [Member]
Apr. 06, 2011
Common Stock Purchase Agreement With Institutional Investors [Member]
Apr. 06, 2011
Consulting Agreement For Financial Advisory Services [Member]
Dec. 31, 2012
Employees and Consultants [Member]
Dec. 31, 2011
Employees and Consultants [Member]
Dec. 31, 2012
Employee [Member]
General And Administrative Expenses And Research And Development Expense [Member]
Dec. 31, 2011
Employee [Member]
General And Administrative Expenses And Research And Development Expense [Member]
Dec. 31, 2012
Consultant [Member]
General And Administrative Expenses And Research And Development Expense [Member]
Dec. 31, 2011
Consultant [Member]
General And Administrative Expenses And Research And Development Expense [Member]
Dec. 31, 2012
2007 Stock Plan [Member]
Mar. 20, 2007
2007 Stock Plan [Member]
Dec. 31, 2012
2010 Stock Plan [Member]
Nov. 02, 2010
2010 Stock Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number     4,453,746 2,979,010 2,539,091   1,066,007                 50,000                           872,739 2,500,000 2,515,000 3,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross           250,000                                   2,075,000 557,002                
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Fair Value                                               $ 4,500,000 $ 609,000                
Issuance Of Warrants To Purchase Of Common Stock 844,391               635,855                       1,428,572 844,391                      
Warrants Exercise Price Per Share   $ 1.00             $ 1.60                       $ 2.00   $ 1.40                    
Life Of Warrants                                     5 years                            
Warrants Expiration Date                                     Dec. 31, 2015                            
Warrants Floor Price Per Share                                       $ 1.40 $ 1.40 $ 1.00                      
Warrant expense 716,000   0 1,492,000       776,000                                                  
Change in fair value of warrant liability     0 242,000                                                          
Options Exercisable, Weighted Average Exercise Price     $ 1.60                         $ 0.001                                  
Options Outstanding, Weighted Average Remaining Contractual Life     6 years 5 months 5 days 6 years 0 months 4 days 6 years 11 months 19 days                     5 years 5 months                                  
Number of Options, Balance exercisable     2,891,877                         40,000                                  
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value                 $ 1.60                                                
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Outstanding Weighted Average Remaining Contractual Terms     3 years 9 months 18 days           5 years               15 months 15 months                              
Investment Warrants Expiration Date                 Oct. 25, 2017                                                
Share Based Compensation Arrangement By Share Based Payment Award Warrants Exercisable Number                   250,000 100,000                                            
Share Based Compensation Arrangement By Share Based Payment Award Warrants Vested and Expected To Vest Outstanding Number                   50,000                                              
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price     $ 0.34 $ 0.57                                                          
Issunance Of Warrants Expenses Recognized                       63,000                                          
Share Based Compensation Arrangement By Share Based Payment Award Warrants Exercisable In Period                   2 years 5 years                                            
Warrants Exercisable Price Per Share                   $ 2.20                                              
Warrants Fair Value       0               200,000                                          
Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized, Stock Options     3,200,000                                                            
Derivative Liability, Fair Value, Gross Liability                         253,000 1,500,000                                      
Increase In Fair Value Of Warrant Liability 765,000                                                                
Share Based Compensation Arrangement By Share Based Payment Award, Warrant Exercisable Price $ 2.0725                                                                
Share Based Compensation Arrangement By Share Based Payment Award, Warrant Exercisable Period 13 months                                                                
Anti Dilution Price Protection Warrants Price Per Share $ 2.0725                                                                
Decrease In Fair Value Of Warrant Liability   523,000                                                              
Allocated Share-Based Compensation Expense                             271,000                     1,400,000 268,000 216,000 705,000        
Employee Service Share-based Compensation, Cash Received from Exercise of Stock Options     $ 127,000 $ 15,000