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Organization and Nature of Operations and Basis of Presentation | 6 Months Ended
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Jun. 30, 2013
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] |
| 1. | Organization and Nature of Operations and Basis of Presentation
Description of Business Synthetic Biologics, Inc. (the “Company” or “Synthetic Biologics”) is a biotechnology company focused on the development of biologics for the prevention and treatment of serious infectious diseases. The Company is developing an oral enzyme for the prevention of C. difficile infections, and a series of monoclonal antibody therapies for the treatment of Pertussis and Acinetobacter infections. In addition, the Company is developing a drug candidate for the treatment of relapsing-remitting multiple sclerosis and cognitive dysfunction in multiple sclerosis, and has partnered the development of a treatment for fibromyalgia.
Therapeutic Area |  | Product Candidate |  | Status
Relapsing-remitting MS |  | Trimesta (oral estriol) |  | Completed enrollment in Phase II clinical trial; dosing and monitoring underway
Cognitive dysfunction in MS |  | Trimesta (oral estriol) |  | Patient enrollment underway in Phase II clinical trial
C. difficile infection prevention |  | SYN-004 (monoclonal antibody) |  | Series of oral enzyme candidates; first generation candidate (formerly known as P1A) is in Phase II; next generation candidate, SYN-004, (formerly known as P3A) is in preclinical
Pertussis |  | SYN-005 (monoclonal antibody) |  | Preclinical; Collaborations with Intrexon and The University of Texas at Austin
Acinetobacter infection |  | SYN-001 (monoclonal antibody) |  | Discovery; Collaboration with Intrexon
Fibromyalgia |  | Effirma (oral flupirtine) |  | Partnered with Meda AB
In order to further prioritize the Company’s focus, it previously elected to discontinue further development of AEN-100 for the treatment of amyotrophic lateral sclerosis. However, the Company is seeking development partners for its zinc-based intellectual property and assets including, AEN-100.

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