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Stock-Based Compensation (Details Textual) (USD $) | 12 Months Ended | 1 Months Ended | 12 Months Ended |  | 12 Months Ended |  | 12 Months Ended
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Dec. 31, 2013 | Dec. 31, 2012 | Oct. 25, 2012 Warrant [Member] | Mar. 15, 2012 Warrant [Member] | Dec. 20, 2011 Warrant [Member] | Dec. 31, 2013 Warrant [Member] | Dec. 31, 2012 Warrant [Member] | Dec. 31, 2013 Epitope [Member] | Dec. 31, 2013 General and Administrative Expenses and Research and Development Expense [Member] Warrant [Member] | Dec. 31, 2012 General and Administrative Expenses and Research and Development Expense [Member] Warrant [Member] | Dec. 31, 2013 Employees And Directors [Member] | Dec. 31, 2012 Employees And Directors [Member] | Dec. 31, 2013 Employee [Member] General and Administrative Expenses and Research and Development Expense [Member] | Dec. 31, 2012 Employee [Member] General and Administrative Expenses and Research and Development Expense [Member] | Dec. 31, 2013 Consultant [Member] General and Administrative Expenses and Research and Development Expense [Member] | Dec. 31, 2012 Consultant [Member] General and Administrative Expenses and Research and Development Expense [Member] | Dec. 31, 2013 2001 Stock Plan [Member] | Dec. 31, 2001 2001 Stock Plan [Member] Maximum [Member] | Dec. 31, 2013 2007 Stock Plan [Member] | Mar. 20, 2007 2007 Stock Plan [Member] | Dec. 31, 2007 2007 Stock Plan [Member] Maximum [Member] | Dec. 31, 2013 2010 Stock Plan [Member] | Nov. 02, 2010 2010 Stock Plan [Member] | Dec. 31, 2013 2010 Stock Plan [Member] Maximum [Member] | Dec. 31, 2013 2010 Stock Plan [Member] Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number |  |  |  |  |  |  |  | 50,000 |  |  |  |  |  |  |  |  | 953,507 |  | 443,573 | 2,500,000 |  | 2,512,500 | 3,000,000 |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | 222,500 |  |  |  |  |  |  |  |  |  | 222,500 | 2,075,000 |  |  |  |  | 953,507 | 250,000 | 443,573 |  | 250,000 | 2,512,500 |  | 6,000,000 | 3,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Fair Value |  |  |  |  |  |  |  |  |  |  | $ 350,000 | $ 4,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Allocated Share-based Compensation Expense |  |  |  |  |  |  |  |  | 0 | 271,000 |  |  | 1,300,000 | 1,400,000 | 324,000 | 216,000 |  |  |  |  |  |  |  |  |
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options | 1,600,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Employee Service Share-based Compensation, Cash Received from Exercise of Stock Options | 231,000 | 127,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of Warrants to Purchase of Common Stock |  |  | 635,855 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms |  |  | 5 years |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants Exercise Price Per Share |  |  | $ 1.60 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Investment Warrants Expiration Date |  |  | Oct. 25, 2017 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Warrants, Exercisable Number |  |  |  | 250,000 | 100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Warrants, Vested and Expected to Vest Outstanding, Number |  |  |  | 50,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants Exercisable Price Per Share |  |  |  | $ 2.20 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Warrants, Exercisable in Period |  |  |  | 2 years | 5 years |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of Warrants Expenses Recognized |  |  |  |  |  | 0 | 63,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Fair Value Warrants |  |  |  |  | $ 200,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number |  |  |  |  |  |  |  | 40,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price |  |  |  |  |  |  |  | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term |  |  |  |  |  |  |  | 4 years 6 months |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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- Definition Fair value of warrants during the period. + References No definition available. + Details
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- Definition Expiration date of warrants held. + References No definition available. + Details
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- Definition Expenses recognized from issuance of warrants. + References No definition available. + Details
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- Definition Warrants issued to purchase common stock. + References No definition available. + Details
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- Definition Fair value of stock (or other type of equity) granted during the period as a result of any equity-based compensation plan other than an employee stock ownership plan (ESOP). + References No definition available. + Details
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- Definition Exercisable term of warrants. + References No definition available. + Details
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- Definition The number of exercisable share warrants that may be converted as of the balance sheet date. + References No definition available. + Details
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- Definition As of the balance sheet date, the number of warrants into which fully vested and expected to vest stock options outstanding can be converted under the option plan. + References No definition available. + Details
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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 -Section F + Details
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- Definition Aggregate proceeds received by the entity during the annual period from exercises of stock or unit options and conversion of similar instruments granted under equity-based payment arrangements. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (j) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Weighted average remaining contractual term for equity-based awards excluding options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Gross number of share options (or share units) granted during the period. + References No definition available. + Details
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- Definition Number of options outstanding, including both vested and non-vested options. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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