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Stock-Based Compensation (Details Textual) (USD $) | 12 Months Ended | 1 Months Ended | 12 Months Ended | 0 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012 | Oct. 25, 2012 | Mar. 15, 2012 | Dec. 20, 2011 | Dec. 31, 2001 | Dec. 31, 2007 | Oct. 10, 2014 | Apr. 03, 2009 | Nov. 02, 2010 | Mar. 20, 2007
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | 2,382,500 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross | 222,500 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross | 2,075,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross |  |  |  |  |  |  |  |  |
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options | $ 4,700,000 us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions |  |  |  |  |  |  |  |  |  |  |
Employee Service Share-based Compensation, Cash Received from Exercise of Stock Options | 4,000 us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions | 232,000 us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions | 2,100,000 us-gaap_EmployeeServiceShareBasedCompensationCashReceivedFromExerciseOfStockOptions |  |  |  |  |  |  |  |  |
Sale of Stock, Price Per Share |  |  |  |  |  |  |  |  |  | $ 5 us-gaap_SaleOfStockPricePerShare |  |
Proceeds from Issuance of Common Stock | 20,668,000 us-gaap_ProceedsFromIssuanceOfCommonStock | 13,224,000 us-gaap_ProceedsFromIssuanceOfCommonStock | 10,800,000 us-gaap_ProceedsFromIssuanceOfCommonStock |  |  |  |  |  |  |  |  |
Change in fair value of warrant liabilities | (620,000)us-gaap_FairValueAdjustmentOfWarrants | 0 us-gaap_FairValueAdjustmentOfWarrants | 0 us-gaap_FairValueAdjustmentOfWarrants |  |  |  |  |  |  |  |  |
Warrant liabilities | 6,756,000 syn_WarrantLiabilities | 0 syn_WarrantLiabilities |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Outstanding | 316,522 us-gaap_ClassOfWarrantOrRightOutstanding |  |  |  |  |  |  |  |  |  |  |
Stock Options Expiration Term | June 2018 |  |  |  |  |  |  |  |  |  |  |
Warrant [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Issuance of Warrants to Purchase of Common Stock |  |  |  | 635,855 syn_IssuanceOfWarrantsToPurchaseOfCommonStock / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |  |  |
Warrants Exercise Price Per Share |  |  |  | $ 1.60 syn_WarrantsExercisePricePerShare / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |  |  |
Investment Warrants Expiration Date |  |  |  | Oct. 25, 2017 |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Warrants, Exercisable Number |  |  |  |  | 250,000 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardWarrantsExercisableNumber / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember | 100,000 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardWarrantsExercisableNumber / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Warrants, Vested and Expected to Vest Outstanding, Number |  |  |  |  | 50,000 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardWarrantsVestedAndExpectedToVestOutstandingNumber / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |  |
Warrants Exercisable Price Per Share |  |  |  |  | $ 2.20 syn_WarrantsExercisablePricePerShare / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |  |
Issuance of Warrants Expenses Recognized | 0 syn_IssuanceOfWarrantsExpensesRecognized / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember | 0 syn_IssuanceOfWarrantsExpensesRecognized / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember | 63,000 syn_IssuanceOfWarrantsExpensesRecognized / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |  |  |  |
Fair Value Warrants |  |  |  |  |  | 200,000 syn_FairValueWarrants / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |
Epitope [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number | 50,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber / dei_LegalEntityAxis = syn_EpitopeMember |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number | 50,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber / dei_LegalEntityAxis = syn_EpitopeMember |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price | $ 0.001 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice / dei_LegalEntityAxis = syn_EpitopeMember |  |  |  |  |  |  |  |  |  |  |
General and Administrative Expenses and Research and Development Expense [Member] | Warrant [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Allocated Share-based Compensation Expense |  |  | 271,000 us-gaap_AllocatedShareBasedCompensationExpense / us-gaap_IncomeStatementLocationAxis = syn_GeneralAndAdministrativeExpensesAndResearchAndDevelopmentExpenseMember / us-gaap_StatementEquityComponentsAxis = us-gaap_WarrantMember |  |  |  |  |  |  |  |  |
Employees And Directors [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | 2,382,500 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeesAndDirectorsMember | 222,500 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeesAndDirectorsMember | 2,075,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeesAndDirectorsMember |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Fair Value | 5,000,000 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodFairValue / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeesAndDirectorsMember | 350,000 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodFairValue / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeesAndDirectorsMember | 4,500,000 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodFairValue / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeesAndDirectorsMember |  |  |  |  |  |  |  |  |
Employee [Member] | General and Administrative Expenses and Research and Development Expense [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Allocated Share-based Compensation Expense | 2,100,000 us-gaap_AllocatedShareBasedCompensationExpense / us-gaap_IncomeStatementLocationAxis = syn_GeneralAndAdministrativeExpensesAndResearchAndDevelopmentExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeeMember | 1,300,000 us-gaap_AllocatedShareBasedCompensationExpense / us-gaap_IncomeStatementLocationAxis = syn_GeneralAndAdministrativeExpensesAndResearchAndDevelopmentExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeeMember | 1,400,000 us-gaap_AllocatedShareBasedCompensationExpense / us-gaap_IncomeStatementLocationAxis = syn_GeneralAndAdministrativeExpensesAndResearchAndDevelopmentExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_EmployeeMember |  |  |  |  |  |  |  |  |
Consultant [Member] | General and Administrative Expenses and Research and Development Expense [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Allocated Share-based Compensation Expense | 380,000 us-gaap_AllocatedShareBasedCompensationExpense / us-gaap_IncomeStatementLocationAxis = syn_GeneralAndAdministrativeExpensesAndResearchAndDevelopmentExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_ConsultantMember | 324,000 us-gaap_AllocatedShareBasedCompensationExpense / us-gaap_IncomeStatementLocationAxis = syn_GeneralAndAdministrativeExpensesAndResearchAndDevelopmentExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_ConsultantMember | 216,000 us-gaap_AllocatedShareBasedCompensationExpense / us-gaap_IncomeStatementLocationAxis = syn_GeneralAndAdministrativeExpensesAndResearchAndDevelopmentExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = syn_ConsultantMember |  |  |  |  |  |  |  |  |
2001 Stock Plan [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number | 682,449 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber / us-gaap_PlanNameAxis = syn_StockPlan2001Member |  |  |  |  |  |  |  |  |  |  |
2001 Stock Plan [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  |  |  |  |  | 250,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_PlanNameAxis = syn_StockPlan2001Member / us-gaap_RangeAxis = us-gaap_MaximumMember |  |  |  |  |
2007 Stock Plan [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number | 428,657 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber / us-gaap_PlanNameAxis = syn_StockPlan2007Member |  |  |  |  |  |  |  |  |  | 3,000,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber / us-gaap_PlanNameAxis = syn_StockPlan2007Member | 2,500,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber / us-gaap_PlanNameAxis = syn_StockPlan2007Member
2007 Stock Plan [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross |  |  |  |  |  |  |  | 250,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_PlanNameAxis = syn_StockPlan2007Member / us-gaap_RangeAxis = us-gaap_MaximumMember |  |  |  |
2010 Stock Plan [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number | 4,870,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber / us-gaap_PlanNameAxis = syn_StockPlan2010Member |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | 682,449 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_PlanNameAxis = syn_StockPlan2010Member |  |  |  |  |  |  |  |  |  |  |
2010 Stock Plan [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | 6,000,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_PlanNameAxis = syn_StockPlan2010Member / us-gaap_RangeAxis = us-gaap_MaximumMember |  |  |  |  |  |  |  |  |  |  |
2010 Stock Plan [Member] | Minimum [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | 3,000,000 us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross / us-gaap_PlanNameAxis = syn_StockPlan2010Member / us-gaap_RangeAxis = us-gaap_MinimumMember |  |  |  |  |  |  |  |  |  |  |
Stock Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Issuance of Warrants to Purchase of Common Stock |  |  |  |  |  |  |  |  | 0.5 syn_IssuanceOfWarrantsToPurchaseOfCommonStock / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |
Investment Warrants Expiration Date |  |  |  |  |  |  |  |  | Oct. 10, 2019 |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Warrants, Exercisable Number |  |  |  |  |  |  |  |  | 7,029,808 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardWarrantsExercisableNumber / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Warrants, Vested and Expected to Vest Outstanding, Number |  |  |  |  |  |  |  |  | 1.75 syn_ShareBasedCompensationArrangementByShareBasedPaymentAwardWarrantsVestedAndExpectedToVestOutstandingNumber / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |
Sale of Stock, Number of Shares Issued in Transaction |  |  |  |  |  |  |  |  | 14,059,616 us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |
Sale of Stock, Price Per Share |  |  |  |  |  |  |  |  | $ 1.47 us-gaap_SaleOfStockPricePerShare / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |
Proceeds from Issuance of Common Stock |  |  |  |  |  |  |  |  | 19,100,000 us-gaap_ProceedsFromIssuanceOfCommonStock / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |
Change in fair value of warrant liabilities | 620,000 us-gaap_FairValueAdjustmentOfWarrants / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |  |  |  |  |  | 7,400,000 us-gaap_FairValueAdjustmentOfWarrants / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |
Warrant liabilities | $ 6,800,000 syn_WarrantLiabilities / us-gaap_PlanNameAxis = syn_StockWarrantsMember |  |  |  |  |  |  |  |  |  |  |

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- Definition Expenses recognized from issuance of warrants. + References No definition available. + Details
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- Definition Warrants issued to purchase common stock. + References No definition available. + Details
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- Definition Fair value of stock (or other type of equity) granted during the period as a result of any equity-based compensation plan other than an employee stock ownership plan (ESOP). + References No definition available. + Details
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- Definition The number of exercisable share warrants that may be converted as of the balance sheet date. + References No definition available. + Details
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- Definition As of the balance sheet date, the number of warrants into which fully vested and expected to vest stock options outstanding can be converted under the option plan. + References No definition available. + Details
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- Definition It represents value of warrant liablities. + References No definition available. + Details
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- Definition Warrants exercisable price per share. + References No definition available. + Details
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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 -Section F + Details
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- Definition Aggregate proceeds received by the entity during the annual period from exercises of stock or unit options and conversion of similar instruments granted under equity-based payment arrangements. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (j) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition The number of shares issued or sold by the subsidiary or equity method investee per stock transaction. + References No definition available. + Details
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- Definition The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Gross number of share options (or share units) granted during the period. + References No definition available. + Details
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- Definition Number of options outstanding, including both vested and non-vested options. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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