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Stock-Based Compensation | 12 Months Ended
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Dec. 31, 2014
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] |
Disclosure of Compensation Related Costs, Share-based Payments [Text Block] | ## 5. Stock-Based Compensation ### Stock Incentive Plan During 2001, the Company’s Board of Directors and stockholders adopted the 2001 Stock Incentive Plan (the “2001 Stock Plan”). The total number of shares of stock with respect to which stock options and stock appreciation rights may be granted to any one employee of the Company or a subsidiary during any one-year period under the 2001 Stock Plan shall not exceed 250,000. All awards pursuant to the 2001 Stock Plan shall terminate upon the termination of the grantee’s employment for any reason. Awards include options, restricted shares, stock appreciation rights, performance shares and cash-based awards (the “Awards”). The 2001 Stock Plan contains certain anti-dilution provisions in the event of a stock split, stock dividend or other capital adjustment, as defined in the plan. The 2001 Stock Plan provides for a Committee of the Board to grant awards and to determine the exercise price, vesting term, expiration date and all other terms and conditions of the awards, including acceleration of the vesting of an award at any time. As of December 31, 2014, there were 682,449 options issued and outstanding under the 2001 Stock Plan. On March 20, 2007, the Company’s Board of Directors approved the 2007 Stock Incentive Plan (the “2007 Stock Plan”) for the issuance of up to 2,500,000 shares of common stock to be granted through incentive stock options, nonqualified stock options, stock appreciation rights, dividend equivalent rights, restricted stock, restricted stock units and other stock-based awards to officers, other employees, directors and consultants of the Company and its subsidiaries. This plan was approved by stockholders on November 2, 2007. The exercise price of stock options under the 2007 Stock Plan is determined by the compensation committee of the Board of Directors, and may be equal to or greater than the fair market value of the Company’s common stock on the date the option is granted. The total number of shares of stock with respect to which stock options and stock appreciation rights may be granted to any one employee of the Company or a subsidiary during any one-year period under the 2007 plan shall not exceed 250,000. Options become exercisable over various periods from the date of grant, and generally expire ten years after the grant date. As of December 31, 2014, there were 428,657 options issued and outstanding under the 2007 Stock Plan. On November 2, 2010, the Board of Directors and stockholders adopted the 2010 Stock Incentive Plan (“2010 Stock Plan”) for the issuance of up to 3,000,000 shares of common stock to be granted through incentive stock options, nonqualified stock options, stock appreciation rights, dividend equivalent rights, restricted stock, restricted stock units and other stock-based awards to officers, other employees, directors and consultants of the Company and its subsidiaries. On October 22, 2013, the stockholders approved and adopted an amendment to the Company’s 2010 Incentive Stock Plan to increase the number of shares of Company’s common stock reserved for issuance under the Plan from 3,000,000 to 6,000,000. The exercise price of stock options under the 2010 Stock Plan is determined by the compensation committee of the Board of Directors, and may be equal to or greater than the fair market value of the Company’s common stock on the date the option is granted. Options become exercisable over various period from the date of grant, and generally expire ten years after the grant date. As of December 31, 2014, there were 4,870,000 options issued and outstanding under the 2010 Stock Plan. In the event of an employee’s termination, the Company will cease to recognize compensation expense for that employee. There is no deferred compensation recorded upon initial grant date, instead, the fair value of the stock-based payment is recognized ratably over the stated vesting period. The Company has applied fair value accounting for all share based payment awards since inception. The fair value of each option or warrant granted is estimated on the date of grant using the Black-Scholes option pricing model. The Black-Scholes assumptions used in the years ended December 31, 2014, 2013 and 2012 are as follows:
|  | Year ended December 31,
|  | 2014 |  | 2013 |  | 2012
Exercise price |  |  | $1.46 – $2.91 |  |  |  | $1.64 – $1.74 |  |  |  | $1.69 – $2.47 |
Expected dividends |  |  | 0% |  |  |  | 0% |  |  |  | 0% |
Expected volatility |  |  | 101% – 150% |  |  |  | 141% – 154% |  |  |  | 108% – 174% |
Risk free interest rate |  |  | 1.57% – 2.73% |  |  |  | 0.77% – 2.54% |  |  |  | 0.37% – 1.98% |
Expected life of option |  |  | 5 years – 10 years |  |  |  | 5 – 10 years |  |  |  | 5 – 10 years |
Expected forfeitures |  |  | 0% |  |  |  | 0% |  |  |  | 0% |
The Company records stock-based compensation based upon the stated vested provisions in the related agreements. The vesting provisions for these agreements have various terms as follows:
| • | immediate vesting,
| • | half vesting immediately and remaining over three years,
| • | quarterly over three years,
| • | annually over three years,
| • | one-third immediate vesting and remaining annually over two years,
| • | one half immediate vesting and remaining over nine months,
| • | one quarter immediate vesting and remaining over three years,
| • | one quarter immediate vesting and remaining over 33 months; and
| • | monthly over three years.
During the years ended December 31, 2014, 2013 and 2012 the Company granted 2,382,500, 222,500 and 2,075,000 options to employees and directors having an approximate fair value of $5.0 million, $350,000 and $4.5 million based upon the Black-Scholes options pricing model, respectively. Stock-based compensation expense included in general and administrative expenses and research and development expenses relating to stock options issued employees for the years ended December 31, 2014, 2013 and 2012 was $2.1 million, $1.3 million and $1.4 million, respectively. Stock-based compensation expense included in general and administrative expenses and research and development expenses relating to stock options issued to consultants for the years ended December 31, 2014, 2013 and 2012 were $380,000, $324,000 and $216,000, respectively. A summary of stock option activities for the years ended December 31, 2014, 2013 and 2012, is as follows:
|  | Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life |  | Aggregate Intrinsic Value
Balance – December 31, 2011 |  |  | 2,979,010 |  |  | $ | 1.34 |  |  |  | 6.01 years |  |  | $ | — |
Granted |  |  | 2,075,000 |  |  | $ | 2.21 |  |  |  |  |  |  |  |  |
Exercised |  |  | (374,851 | ) |  | $ | 0.34 |  |  |  |  |  |  | $ | 661,000 |
Forfeited |  |  | (225,413 | ) |  | $ | 2.37 |  |  |  |  |  |  |  |  |
Balance – December 31, 2012 |  |  | 4,453,746 |  |  | $ | 1.78 |  |  |  | 6.43 years |  |  | $ | 1,308,000 |
Granted |  |  | 222,500 |  |  | $ | 1.69 |  |  |  |  |  |  |  |  |
Exercised |  |  | (291,666 | ) |  | $ | 0.79 |  |  |  |  |  |  | $ | 71,000 |
Forfeited |  |  | (475,000 | ) |  | $ | 2.30 |  |  |  |  |  |  |  |  |
Balance – December 31, 2013 |  |  | 3,909,580 |  |  | $ | 1.78 |  |  |  | 5.59 years |  |  | $ | 785,000 |
Granted |  |  | 2,382,500 |  |  | $ | 2.36 |  |  |  |  |  |  |  |  |
Exercised |  |  | (6,583 | ) |  | $ | 0.58 |  |  |  |  |  |  | $ | 8,000 |
Forfeited |  |  | (304,391 | ) |  | $ | 1.93 |  |  |  |  |  |  |  |  |
Balance – December 31, 2014 – outstanding |  |  | 5,981,106 |  |  | $ | 2.01 |  |  |  | 5.80 years |  |  | $ | 685,000 |
Balance – December 31, 2014 – exercisable |  |  | 3,893,196 |  |  | $ | 1.85 |  |  |  | 5.12 years |  |  | $ | 685,000 |
Grant date fair value of options granted – 2014 |  |  |  |  |  | $ | 4,974,000 |  |  |  |  |  |  |  |  |
Weighted average grant date fair value – 2014 |  |  |  |  |  | $ | 2.09 |  |  |  |  |  |  |  |  |
Grant date fair value of options granted – 2013 |  |  |  |  |  | $ | 350,000 |  |  |  |  |  |  |  |  |
Weighted average grant date fair value – 2013 |  |  |  |  |  | $ | 1.57 |  |  |  |  |  |  |  |  |
Grant date fair value of options granted – 2012 |  |  |  |  |  | $ | 4,468,000 |  |  |  |  |  |  |  |  |
Weighted average grant date fair value – 2012 |  |  |  |  |  | $ | 2.15 |  |  |  |  |  |  |  |  |
The options outstanding and exercisable at December 31, 2014 are as follows:
|  | Options Outstanding |  | Options Exercisable
|  | Range of Exercise Price |  | Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life |  | Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life
|  | $ | 0.09 – $2.00 |  |  |  | 2,703,280 |  |  | $ | 1.37 |  |  |  | 4.33 years |  |  |  | 2,018,074 |  |  | $ | 1.28 |  |  |  | 3.73 years |
|  | $ | 2.01 – $3.00 |  |  |  | 3,232,002 |  |  |  | 2.49 |  |  |  | 7.08 years |  |  |  | 1,829,298 |  |  |  | 2.40 |  |  |  | 6.73 years |
|  | $ | 3.01 – $6.00 |  |  |  | 45,824 |  |  |  | 5.24 |  |  |  | 2.62 years |  |  |  | 45,824 |  |  |  | 5.24 |  |  |  | 2.62 years |
|  | $ | 0.09 – $6.00 |  |  |  | 5,981,106 |  |  | $ | 2.01 |  |  |  | 5.80 years |  |  |  | 3,893,196 |  |  | $ | 1.85 |  |  |  | 5.12 years |
The options outstanding and exercisable at December 31, 2013 are as follows:
|  | Options Outstanding |  | Options Exercisable
|  | Range of Exercise Price |  | Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life |  | Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life
|  | $ | 0.09 – $2.00 |  |  |  | 2,093,196 |  |  | $ | 1.29 |  |  |  | 4.73 years |  |  |  | 1,901,737 |  |  | $ | 1.25 |  |  |  | 4.64 years |
|  | $ | 2.01 – $3.00 |  |  |  | 1,770,560 |  |  |  | 2.28 |  |  |  | 6.65 years |  |  |  | 1,205,976 |  |  |  | 2.26 |  |  |  | 6.25 years |
|  | $ | 3.01 – $6.00 |  |  |  | 45,824 |  |  |  | 5.24 |  |  |  | 3.62 years |  |  |  | 45,824 |  |  |  | 5.24 |  |  |  | 3.62 years |
|  | $ | 0.09 – $6.00 |  |  |  | 3,909,580 |  |  | $ | 1.78 |  |  |  | 5.59 years |  |  |  | 3,153,537 |  |  | $ | 1.69 |  |  |  | 5.24 years |
The options outstanding and exercisable at December 31, 2012 are as follows:
|  | Options Outstanding |  | Options Exercisable
|  | Range of Exercise Price |  | Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life |  | Options |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life
|  | $ | 0.09 – $2.00 |  |  |  | 2,162,362 |  |  | $ | 1.78 |  |  |  | 5.76 years |  |  |  | 1,801,187 |  |  | $ | 1.14 |  |  |  | 5.52 years |
|  | $ | 2.01 – $3.00 |  |  |  | 2,212,227 |  |  |  | 2.26 |  |  |  | 7.15 years |  |  |  | 1,011,533 |  |  |  | 2.17 |  |  |  | 6.14 years |
|  | $ | 3.01 – $6.00 |  |  |  | 79,157 |  |  |  | 4.87 |  |  |  | 4.49 years |  |  |  | 79,157 |  |  |  | 4.87 |  |  |  | 4.49 years |
|  | $ | 0.09 – $6.00 |  |  |  | 4,453,746 |  |  | $ | 1.78 |  |  |  | 6.43 years |  |  |  | 2,891,877 |  |  | $ | 1.60 |  |  |  | 5.71 years |
The following is a summary of the Company’s non-vested stock options at December 31, 2014:
|  | Unvested Stock Options |  | Weighted Average Grant Date Fair Value
Non-vested – December 31, 2011 |  |  | 524,403 |  |  | $ | 0.82 |
Granted |  |  | 2,075,000 |  |  |  | 2.21 |
Vested/Exercised |  |  | (891,332 | ) |  |  | 0.81 |
Forfeited/Cancelled |  |  | (146,202 | ) |  |  | 1.79 |
Non-vested – December 31, 2012 |  |  | 1,561,869 |  |  | $ | 2.11 |
Granted |  |  | 222,500 |  |  |  | 1.69 |
Vested/Exercised |  |  | (883,882 | ) |  |  | 1.93 |
Forfeited/Cancelled |  |  | (144,444 | ) |  |  | 2.27 |
Non-vested – December 31, 2013 |  |  | 756,043 |  |  |  | 2.17 |
Granted |  |  | 2,382,500 |  |  |  | 2.36 |
Vested/Exercised |  |  | (1,050,633 | ) |  |  | 2.35 |
Non-vested – December 31, 2014 |  |  | 2,087,910 |  |  | $ | 2.30 |
Weighted average remaining period for vesting |  |  | 2.15 years |  |  |  |  |
As of December 31, 2014, total unrecognized stock-based compensation expense related to stock options was $4.7 million, which is expected to be expensed through December 2017. FASB’s guidance for stock-based payments requires cash flows from excess tax benefits to be classified as a part of cash flows from financing activities. Excess tax benefits are realized tax benefits from tax deductions for exercised options in excess of the deferred tax asset attributable to stock compensation costs for such options. The Company did not record any excess tax benefits in 2014, 2013 or 2012. Cash received from option exercises under the Company’s stock-based compensation plans for the years ended December 31, 2014, 2013 and 2012 was $4,000, $232,000 and $2.1 million, respectively.
### Stock Warrants On October 10, 2014, the Company raised net proceeds of $19.1 million through the sale of 14,059,616 units at a price of $1.47 per unit to certain institutional investors in a registered direct offering. Each unit consisted of one share of the Company’s common stock and a warrant to purchase 0.5 shares of common stock. The warrants, exercisable for an aggregate of 7,029,808 shares of common stock, have an exercise price of $1.75 per share and a life of five years. The warrants vested immediately and expire October 10, 2019. The warrants issued in conjunction with the registered direct offering in October 2014 include a provision, that if the Company were to enter into a certain transaction, as defined in the agreement, the warrants would be purchased from the holder at a premium. Accordingly, the Company recorded the warrants as a liability at their estimated fair value on the issuance date, which was $7.4 million, and changes in estimated fair value will be recorded as non-cash income or expense in the Company’s statement of operations at each subsequent period. At December 31, 2014, the fair value of the warrant liability was $6.8 million, which represented non-cash income of $620,000. In accordance with authoritative accounting guidance, the warrant was valued on the date of grant using the Black-Scholes valuation model. The assumptions used by the Company are summarized in the following table:
|  | Issuance Date |  | December 31, 2014
Closing stock price |  |  | $1.75 |  |  |  | $1.46 |
Expected dividends |  |  | 0 | % |  |  | 0 | %
Expected volatility |  |  | 95 | % |  |  | 90 | %
Risk free interest rate |  |  | 1.39 | % |  |  | 1.59 | %
Expected life of warrant |  |  | 5 years |  |  |  | 4.79 years |
The following table summarizes the estimated fair value of the warrant liability (in thousands):
Balance at December 31, 2013 |  | $ | — |
Warrants liability |  |  | 7,376 |
Change in fair value of warrant liability |  |  | (620 | )
Balance at December 31, 2014 |  | $ | 6,756 |
As of December 31, 2014, all of the warrants remained outstanding. On October 25, 2012, the Company entered into a Common Stock Purchase Agreement with certain accredited investors. As part of this agreement, the Company issued warrants to purchase 635,855 shares of common stock to the placement agent, or its permitted assigns. The warrants have an exercise price of $1.60 and a life of five years. The warrants vested immediately and expire October 25, 2017. Since these warrants were granted as part of an equity raise, the Company has treated them as a direct offering cost. The result of the transaction has no affect to equity. As of December 31, 2014, 316,522 warrants were outstanding. On March 15, 2012, the Company entered into a consulting agreement for a financial communications program, for a period of 12 months that began on February 20, 2012, which was extended to March 14, 2014. As compensation for such program, the consultant is paid a monthly fee and will be issued a performance warrant exercisable for 250,000 shares of the Company’s common stock based on achievement of certain stock price milestones through March 14, 2013. In March 2013, the Company extended the period to which the milestones could be achieved to March 14, 2014. Upon initiation of the program, 50,000 of the performance warrants vested. The performance warrant is exercisable for a period of two years from the date of issuance for an exercise price equal to the price ($2.20 per share) of the Company’s common stock on the date of execution (March 15, 2012). The expense recorded for the years ended December 31, 2014, 2013 and 2012 approximated $0, $0 and $63,000, respectively, and was estimated using the Monte Carlo valuation model. The assumptions used by the Company are summarized in the following table:
Exercise price |  |  | $2.20 |
Expected dividends |  |  | 0 | %
Expected volatility |  |  | 110 | %
Risk free interest rate |  |  | 0.26 | %
Expected life of warrant |  |  | 2 years |
These warrants expired unexercised in March 2014. On December 20, 2011, the Company entered into a consulting agreement for financial advisory services, for a period of 12 months. As compensation for such services, the consultant is paid a monthly fee and on February 2, 2012, was issued a warrant exercisable for 100,000 shares of the Company’s common stock. The warrant was exercisable upon issuance for a period of five years from the date of issue at an exercise price equal to the price of the Company’s common stock on the date of issue. The fair value of the warrant approximated $200,000 and was measured using the Black-Scholes valuation model. All of this expense was recorded in the year ended December 31, 2012. The assumptions used by the Company are summarized in the following table:
Exercise price |  |  | $1.14 |
Expected dividends |  |  | 0 | %
Expected volatility |  |  | 174 | %
Risk free interest rate |  |  | 0.71 | %
Expected life of warrant |  |  | 5 years |
At December 31, 2014, none of these warrants were outstanding. A summary of warrant activity for the Company for the years ended December 31, 2014, 2013 and 2012 is as follows:
|  | Number of Warrants |  | Weighted Average Exercise Price
Balance at December 31, 2011 |  |  | 3,259,186 |  |  | $ | 1.95 |
Granted |  |  | 985,855 |  |  | $ | 1.71 |
Exercised |  |  | (1,768,167 | ) |  | $ | 1.11 |
Forfeited |  |  | (844,373 | ) |  | $ | 3.32 |
Balance at December 31, 2012 |  |  | 1,632,501 |  |  | $ | 1.99 |
Granted |  |  | — |  |  | $ | — |
Exercised |  |  | — |  |  | $ | — |
Forfeited |  |  | — |  |  | $ | — |
Balance at December 31, 2013 |  |  | 1,632,501 |  |  | $ | 1.99 |
Granted |  |  | 7,029,808 |  |  | $ | 1.75 |
Exercised |  |  | (232,619 | ) |  | $ | 1.47 |
Forfeited |  |  | (454,896 | ) |  | $ | 1.88 |
Balance at December 31, 2014 |  |  | 7,974,794 |  |  | $ | 1.80 |
There was no stock-based compensation expense included in general and administrative expenses relating to warrants issued to consultants for the years ended December 31, 2014 and 2013. Stock-based compensation expense included in general and administrative expenses relating to warrants issued to consultants for the year ended December 31, 2012 was $271,000. A summary of all outstanding and exercisable warrants as of December 31, 2014 is as follows:
|  | Exercise Price |  | Warrants Outstanding |  | Warrants Exercisable |  | Weighted Average Remaining Contractual Life
|  |  | $1.60 |  |  |  | 316,522 |  |  |  | 316,522 |  |  |  | 2.82 years |
|  |  | $1.75 |  |  |  | 7,029,808 |  |  |  | 7,029,808 |  |  |  | 4.78 years |
|  |  | $2.22 |  |  |  | 517,257 |  |  |  | 517,257 |  |  |  | 1.91 years |
|  |  | $3.30 |  |  |  | 61,207 |  |  |  | 61,207 |  |  |  | 0.41 years |
|  |  | $3.75 |  |  |  | 50,000 |  |  |  | 50,000 |  |  |  | 1.13 years |
|  |  | $1.99 |  |  |  | 7,974,794 |  |  |  | 7,974,794 |  |  |  | 4.46 years |
### Options of Subsidiary As of December 31, 2014, Epitope, a majority-owned subsidiary of Synthetic Biologics, has 50,000 stock options outstanding and exercisable. These stock options have an exercise price of $0.001 and expire in June 2018.

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- Definition The entire disclosure for compensation-related costs for equity-based compensation, which may include disclosure of policies, compensation plan details, allocation of equity compensation, incentive distributions, equity-based arrangements to obtain goods and services, deferred compensation arrangements, employee stock ownership plan details and employee stock purchase plan details. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6406099&loc=d3e25284-112666 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 40 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6418621&loc=d3e17540-113929 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5444-113901 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 + Details
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