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v2.4.1.9

Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified | 12 Months Ended
--- | ---
Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012
Cash Flows From Operating Activities: |  |  |
Net loss | $ (19,784)us-gaap_ProfitLoss | $ (12,318)us-gaap_ProfitLoss | $ (17,068)us-gaap_ProfitLoss
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Stock-based compensation | 2,459 us-gaap_ShareBasedCompensation | 1,669 us-gaap_ShareBasedCompensation | 1,851 us-gaap_ShareBasedCompensation
Stock issued for exclusive channel collaboration agreement | 0 syn_IssueOfStockForExclusiveChannelCollaborationAgreement | 0 syn_IssueOfStockForExclusiveChannelCollaborationAgreement | 7,815 syn_IssueOfStockForExclusiveChannelCollaborationAgreement
Stock issued for acquisition of program assets | 0 syn_StockIssuedForAcquisitionsOfProgramAssets | 0 syn_StockIssuedForAcquisitionsOfProgramAssets | 1,169 syn_StockIssuedForAcquisitionsOfProgramAssets
Stock issued for license agreement | 0 syn_StockIssuedForLicenseAgreement | 425 syn_StockIssuedForLicenseAgreement | 0 syn_StockIssuedForLicenseAgreement
Change in fair value of warrant liabilities | (620)us-gaap_FairValueAdjustmentOfWarrants | 0 us-gaap_FairValueAdjustmentOfWarrants | 0 us-gaap_FairValueAdjustmentOfWarrants
Depreciation | 20 us-gaap_Depreciation | 43 us-gaap_Depreciation | 63 us-gaap_Depreciation
Provision for uncollectible accounts receivable | 0 syn_ProvisionForUncollectibleAccountsReceivable | 0 syn_ProvisionForUncollectibleAccountsReceivable | 442 syn_ProvisionForUncollectibleAccountsReceivable
Provision for uncollectible note and interest receivables | 0 syn_ProvisionForUncollectibleNoteAndInterestReceivables | 763 syn_ProvisionForUncollectibleNoteAndInterestReceivables | 0 syn_ProvisionForUncollectibleNoteAndInterestReceivables
Loss on sale of equipment | 0 us-gaap_GainLossOnDispositionOfAssets | 58 us-gaap_GainLossOnDispositionOfAssets | 0 us-gaap_GainLossOnDispositionOfAssets
Impairment loss on equipment | 0 syn_EquipmentImpairmentLoss | 121 syn_EquipmentImpairmentLoss | 47 syn_EquipmentImpairmentLoss
Gain on sale of discontinued operations | 0 syn_GainLossOnSaleOfDiscontinuedOperation | 0 syn_GainLossOnSaleOfDiscontinuedOperation | (677)syn_GainLossOnSaleOfDiscontinuedOperation
Changes in operating assets and liabilities: |  |  |
Accounts receivable | 0 us-gaap_IncreaseDecreaseInAccountsReceivable | 0 us-gaap_IncreaseDecreaseInAccountsReceivable | 14 us-gaap_IncreaseDecreaseInAccountsReceivable
Prepaid expenses and other current assets | 43 us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | 855 us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | (2,544)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Deposits and other assets | (2)syn_IncreaseDecreaseInDepositsAndOtherAssets | 33 syn_IncreaseDecreaseInDepositsAndOtherAssets | (6)syn_IncreaseDecreaseInDepositsAndOtherAssets
Accounts payable | 854 us-gaap_IncreaseDecreaseInAccountsPayable | (253)us-gaap_IncreaseDecreaseInAccountsPayable | 7 us-gaap_IncreaseDecreaseInAccountsPayable
Accrued expenses | 416 us-gaap_IncreaseDecreaseInAccruedLiabilities | 885 us-gaap_IncreaseDecreaseInAccruedLiabilities | (29)us-gaap_IncreaseDecreaseInAccruedLiabilities
Accrued employee benefits | 535 us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities | 0 us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities | 0 us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities
Net Cash Used In Operating Activities | (16,079)us-gaap_NetCashProvidedByUsedInOperatingActivities | (7,719)us-gaap_NetCashProvidedByUsedInOperatingActivities | (8,916)us-gaap_NetCashProvidedByUsedInOperatingActivities
Cash Flows From Investing Activities: |  |  |
Purchases of property and equipment | (48)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (36)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (10)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Net Cash Used In Investing Activities | (48)us-gaap_NetCashProvidedByUsedInInvestingActivities | (36)us-gaap_NetCashProvidedByUsedInInvestingActivities | (10)us-gaap_NetCashProvidedByUsedInInvestingActivities
Cash Flows From Financing Activities: |  |  |
Proceeds from issuance of common stock for stock option exercises | 4 syn_ProceedsFromIssuanceOfCommonStockForStockOptionAndWarrantsExercises | 232 syn_ProceedsFromIssuanceOfCommonStockForStockOptionAndWarrantsExercises | 2,082 syn_ProceedsFromIssuanceOfCommonStockForStockOptionAndWarrantsExercises
Proceeds from issuance of common stock | 20,668 us-gaap_ProceedsFromIssuanceOfCommonStock | 13,224 us-gaap_ProceedsFromIssuanceOfCommonStock | 10,800 us-gaap_ProceedsFromIssuanceOfCommonStock
Cash paid as direct offering costs | (1,645)syn_DirectOfferingCost | (1,031)syn_DirectOfferingCost | (680)syn_DirectOfferingCost
Cash received from issuance of stock to non-controlling interest | 0 us-gaap_ProceedsFromMinorityShareholders | 1 us-gaap_ProceedsFromMinorityShareholders | 0 us-gaap_ProceedsFromMinorityShareholders
Net Cash Provided By Financing Activities | 19,027 us-gaap_NetCashProvidedByUsedInFinancingActivities | 12,426 us-gaap_NetCashProvidedByUsedInFinancingActivities | 12,202 us-gaap_NetCashProvidedByUsedInFinancingActivities
Net increase in cash | 2,900 us-gaap_CashPeriodIncreaseDecrease | 4,671 us-gaap_CashPeriodIncreaseDecrease | 3,276 us-gaap_CashPeriodIncreaseDecrease
Cash at beginning of period | 14,625 us-gaap_CashAndCashEquivalentsAtCarryingValue | 9,954 us-gaap_CashAndCashEquivalentsAtCarryingValue | 6,678 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash at end of period | 17,525 us-gaap_CashAndCashEquivalentsAtCarryingValue | 14,625 us-gaap_CashAndCashEquivalentsAtCarryingValue | 9,954 us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosures of cash flow information: |  |  |
Cash paid for interest | 0 us-gaap_InterestPaid | 0 us-gaap_InterestPaid | 0 us-gaap_InterestPaid
Cash paid for taxes | $ 0 us-gaap_IncomeTaxesPaid | $ 0 us-gaap_IncomeTaxesPaid | $ 0 us-gaap_IncomeTaxesPaid

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- Definition The consolidated profit or loss for the period, net of income taxes, including the portion attributable to the noncontrolling interest. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 55 -Paragraph 4K -URI http://asc.fasb.org/extlink&oid=35736750&loc=SL4591552-111686 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 45 -Paragraph 19 -URI http://asc.fasb.org/extlink&oid=7656940&loc=SL4569616-111683 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 50 -Paragraph 1A -Subparagraph (a),(c) -URI http://asc.fasb.org/extlink&oid=18733093&loc=SL4573702-111684 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 810 -SubTopic 10 -Section 55 -Paragraph 4J -URI http://asc.fasb.org/extlink&oid=35736750&loc=SL4591551-111686 + Details
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