<SEC-DOCUMENT>0001140361-15-034454-index.html : 20150904
<SEC-HEADER>0001140361-15-034454.hdr.sgml : 20150904
<ACCEPTANCE-DATETIME>20150904143754
ACCESSION NUMBER:		0001140361-15-034454
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20150904
DATE AS OF CHANGE:		20150904
GROUP MEMBERS:		INTREXON CORP
GROUP MEMBERS:		NRM VII HOLDINGS I, LLC
GROUP MEMBERS:		THIRD SECURITY, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Synthetic Biologics, Inc.
		CENTRAL INDEX KEY:			0000894158
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				133808303
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-50777
		FILM NUMBER:		151094362

	BUSINESS ADDRESS:	
		STREET 1:		617 DETROIT STREET, SUITE 100
		CITY:			ANN ARBOR
		STATE:			MI
		ZIP:			48104
		BUSINESS PHONE:		(734) 332-7800

	MAIL ADDRESS:	
		STREET 1:		155 GIBBS STREET
		STREET 2:		SUITE 412
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADEONA PHARMACEUTICALS, INC.
		DATE OF NAME CHANGE:	20081027

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PIPEX PHARMACEUTICALS, INC.
		DATE OF NAME CHANGE:	20061214

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHEFFIELD PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19970730

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			KIRK RANDAL J
		CENTRAL INDEX KEY:			0001091823

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	MAIL ADDRESS:	
		STREET 1:		1881 GROVE AVENUE
		CITY:			RADFORD
		STATE:			VA
		ZIP:			24141
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>formsc13da.htm
<DESCRIPTION>RANDAL J. KIRK SC 13DA NO 4 9-2-2015 (SYNTHETIC BIOLOGICS)
<TEXT>
Document 1 - file: formsc13da.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-2
<SEQUENCE>2
<FILENAME>ex2.htm
<DESCRIPTION>EXHIBIT 2
<TEXT>
Document 2 - file: ex2.htm

</DOCUMENT>
</SEC-DOCUMENT>