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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2017
Income Tax Disclosure [Abstract] |
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] | The Company’s tax expense differs from the “expected” tax expense for the years ended December 31, 2017 and 2016 (computed by applying the Federal corporate tax rate of 34% to loss before taxes and 3.96% for blended state income tax rate, the blended rate used was 37.96%), as follows (in thousands):
|  | 2017 |  | 2016 |
Computed “expected” tax-benefit – Federal |  | $ | (5,267) |  | $ | (9,453) |
Computed “expected” tax-benefit – State |  |  | (613) |  |  | (1,101) |
Adjustment of “expected” tax-benefit to actual |  |  | (2) |  |  | (431) |
Meals, entertainment and other |  |  | 10 |  |  | 10 |
Non-deductible stock-based compensation |  |  | 502 |  |  | 574 |
Fair Market Value Adjustment – Warrants |  |  | (4,076) |  |  | (4,332) |
Impact of U.S. tax reform |  |  | 21,555 |  |  | - |
Change in valuation allowance |  |  | (12,109) |  |  | 14,733 |
|  | $ | — |  | $ | — |
Schedule of Deferred Tax Assets and Liabilities [Table Text Block] | The effects of temporary differences that gave rise to significant portions of deferred tax assets at December 31, 2017 and 2016 are as follows (in thousands ):
|  | 2017 |  | 2016 |
Deferred tax assets: |  |  |  |  |  |  |
Stock issued for services |  | $ | 1,730 |  | $ | 1,861 |
Accrued compensation |  |  | 164 |  |  | 119 |
Stock issued for acquisition of program |  |  | 1,202 |  |  | 1,576 |
Stock issued for license agreement |  |  | 1,947 |  |  | 3,147 |
Stock issued for milestone payment |  |  | 301 |  |  | 478 |
Amortizable license fee |  |  | 6 |  |  | 9 |
Net operating loss carry-forward |  |  | 40,248 |  |  | 50,517 |
Total gross deferred tax assets |  |  | 45,598 |  |  | 57,707 |
Less: valuation allowance |  |  | (45,598) |  |  | (57,707) |
Total net deferred tax assets |  | $ | — |  | $ | — |

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- Definition Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32639-109319 + Details
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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32537-109319 + Details
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