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Selected Balance Sheet Information (Tables) | 3 Months Ended
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Mar. 31, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
Schedule of Other Current Assets [Table Text Block] | Prepaid expenses and other current assets (in thousands)
|  | March 31, 2019 |  |  | December 31, 2018 |
Prepaid manufacturing expenses |  | $ | 415 |  |  | $ | - |
Prepaid insurances |  |  | 287 |  |  |  | 419 |
Prepaid consulting, subscriptions and other expenses |  |  | 127 |  |  |  | 132 |
Prepaid clinical research organizations |  |  | 22 |  |  |  | - |
Prepaid conferences, travel |  |  | 3 |  |  |  | 42 |
Other receivables |  |  | 6 |  |  |  | - |
Total |  | $ | 860 |  |  | $ | 593 |
Property, Plant and Equipment [Table Text Block] | Property and equipment, net (in thousands)
|  | March 31, 2019 |  |  | December 31, 2018 |
Computers and office equipment |  | $ | 852 |  |  | $ | 852 |
Leasehold improvements |  |  | 439 |  |  |  | 439 |
Software |  |  | 11 |  |  |  | 11 |
|  |  | 1,302 |  |  |  | 1,302 |
Less: accumulated depreciation and amortization |  |  | (757 | ) |  |  | (695 | )
Total |  | $ | 545 |  |  | $ | 607 |
Accrued Expenses [Table Text Block] | Accrued expenses (in thousands)
|  | March 31, 2019 |  |  | December 31, 2018 |
Accrued manufacturing costs |  | $ | 705 |  |  | $ | 83 |
Accrued clinical consulting services |  |  | 690 |  |  |  | 674 |
Accrued vendor payments |  |  | 229 |  |  |  | 150 |
Other accrued expenses |  |  | 6 |  |  |  | 12 |
Total |  | $ | 1,630 |  |  | $ | 919 |
Accrued Employee Benefits [Table Text Block] | Accrued employee benefits (in thousands)
|  | March 31, 2019 |  |  | December 31, 2018 |
Accrued bonus expense |  | $ | 215 |  |  | $ | 907 |
Accrued vacation expense |  |  | 124 |  |  |  | 118 |
Accrued severance |  |  | 2 |  |  |  | 307 |
Total |  | $ | 341 |  |  | $ | 1,332 |

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- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(13)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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