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Consolidated Statements of (Deficit) Equity - USD ($) $ in Thousands | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Deficit [Member] | Noncontrolling Interest [Member] | Series B Preferred Stock [Member] | Total
--- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2017 | $ 4 | $ 192,670 | $ (194,170) | $ (1,914) | $ 0 | $ (3,410)
Balance (in shares) at Dec. 31, 2017 | 3,671,014 |  |  |  | 0 |
Stock-based compensation | $ 0 | 2,074 | 0 | 0 | $ 0 | 2,074
Stock issued under "at-the-market" offering | $ 3 | 12,169 | 0 | 0 | 0 | 12,172
Stock issued under "at-the-market" offering (in shares) | 3,534,982 |  |  |  |  |
Common stock and warrants issued to vendors | $ 0 | 35 | 0 | 0 | 0 | 35
Common stock and warrants issued to vendors (in Shares) | 50,000 |  |  |  |  |
Series A Preferred Stock Dividends | $ 0 | 0 | (243) | 0 | $ 0 | (243)
Stock issued for exercise of stock options (in shares) |  |  |  |  | 0 |
Series B preferred stock beneficial conversion feature discount | 0 | 0 | (9,161) | 0 | $ 9,161 | 0
Issuance of Common Stock, preferred Stock and Warrants in Units Offering, net of issuance costs | $ 2 | 16,273 | 0 | 0 | $ 641 | 16,916
Issuance of Common Stock, preferred Stock and Warrants in Units Offering, net of issuance costs (in shares) | 2,520,000 |  |  |  | 15,723 |
Issuance of SYN Biomics Stock | $ 0 | 977 | 0 | (941) | $ 0 | 36
Conversion of Series B Preferred Stock to Common | $ 6 | 6,556 | (2,520) | 0 | $ (4,042) | 0
Conversion of Series B Preferred Stock to Common (in shares) | 5,706,087 |  |  |  | (6,562) |
Net loss | $ 0 | 0 | (13,367) | 0 | $ 0 | (13,367)
Non-controlling interest | 0 | 0 | 0 | (54) | 0 | (54)
Balance at Dec. 31, 2018 | $ 15 | 230,754 | (219,461) | (2,909) | $ 5,760 | 14,159
Balance (in shares) at Dec. 31, 2018 | 15,482,083 |  |  |  | 9,161 |
Stock-based compensation | $ 0 | 340 | 0 | 0 | $ 0 | 340
Series A Preferred Stock Dividends | 0 | 0 | (248) | 0 | 0 | (248)
Issuance of SYN Biomics Stock | 0 | (36) | 0 | 108 | 0 | 72
Conversion of Series B Preferred Stock to Common | $ 2 | 1,522 | (525) | 0 | $ (999) | 0
Conversion of Series B Preferred Stock to Common (in shares) | 1,324,347 |  |  |  | (1,523) |
Net loss | $ 0 | 0 | (15,303) | 0 | $ 0 | (15,303)
Non-controlling interest | 0 | 0 | 0 | (77) | 0 | (77)
Balance at Dec. 31, 2019 | $ 17 | $ 232,580 | $ (235,537) | $ (2,878) | $ 4,761 | $ (1,057)
Balance (in shares) at Dec. 31, 2019 | 16,806,430 |  |  |  | 7,638 |

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