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Consolidated Statements of Stockholders Deficit - USD ($) $ in Thousands | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Deficit [Member] | Noncontrolling Interest [Member] | Series B Preferred Stock [Member] | Total
--- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2018 | $ 15 | $ 230,754 | $ (219,461) | $ (2,909) | $ 5,760 | $ 14,159
Balance (in shares) at Dec. 31, 2018 | 15,482,083 |  |  |  | 9,161 |
Stock-based compensation | $ 0 | 340 | 0 | 0 | $ 0 | 340
Series A Preferred Stock Dividends | 0 | 0 | (248) | 0 | 0 | (248)
Issuance of SYN Biomics Stock | $ 0 | (36) | 0 | 108 | $ 0 | 72
Conversion of Series B Preferred Stock to Common (in shares) | 1,324,347 |  |  |  | (1,523) |
Conversion of Series B Preferred Stock to Common | $ 2 | 1,522 | (525) | 0 | $ (999) | 0
Net loss | 0 | 0 | (15,303) | 0 | 0 | (15,303)
Non-controlling interest | 0 | 0 | 0 | (77) | 0 | (77)
Balance at Dec. 31, 2019 | $ 17 | 232,580 | (235,537) | (2,878) | $ 4,761 | (1,057)
Balance (in shares) at Dec. 31, 2019 | 16,806,430 |  |  |  | 7,638 |
Stock-based compensation | $ 0 | 350 | 0 | 0 | $ 0 | 350
Stock issued under "at-the-market" offering | $ 9 | 3,350 | 0 | 0 | 0 | 3,359
Stock issued under "at-the-market" offering (in shares) | 9,256,535 |  |  |  |  |
Series A Preferred Stock Dividends | $ 0 | 0 | (254) | 0 | 0 | (254)
Issuance of SYN Biomics Stock | 0 | 0 | 0 | 178 | 0 | 178
Effect of Warrant exercise price adjustment | $ 0 | 880 | (880) | 0 | $ 0 | 0
Conversion of Series B Preferred Stock to Common (in shares) | 3,186,960 |  |  |  | (3,665) |
Conversion of Series B Preferred Stock to Common | $ 3 | 3,661 | (1,380) | 0 | $ (2,284) | 0
Net loss | 0 | 0 | (10,043) | 0 | 0 | (10,043)
Non-controlling interest | 0 | 0 | 0 | (73) | 0 | (73)
Balance at Dec. 31, 2020 | $ 29 | $ 240,821 | $ (248,094) | $ (2,773) | $ 2,477 | $ (7,540)
Balance (in shares) at Dec. 31, 2020 | 29,249,925 |  |  |  | 3,973 |

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