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Selected Balance Sheet Information - Schedule of Accrued expenses (Details) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021
--- | --- | ---
Selected Balance Sheet Information |  |
Accrued clinical consulting services | $ 807 | $ 696
Accrued vendor payments | 492 | 1,028
Accrued manufacturing costs | 197 | 204
Total | $ 1,496 | $ 1,928

X
- Definition The carrying value of accrued clinical consulting services payable as on balance sheet date. + References No definition available. + Details
Name: | syn_AccruedClinicalConsultingServices
Namespace Prefix: | syn_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

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- Definition Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). + References No definition available. + Details
Name: | syn_AccruedLiabilitiesCurrent.
Namespace Prefix: | syn_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition The manufacturing costs incurred in the production of goods for sale. + References No definition available. + Details
Name: | syn_AccruedManufacturingCosts
Namespace Prefix: | syn_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Carrying value as of the balance sheet date of obligations and payables pertaining to vendor payments. + References No definition available. + Details
Name: | syn_AccruedVendorPayments
Namespace Prefix: | syn_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- References No definition available. + Details
Name: | syn_BalanceSheetInformationAbstract
Namespace Prefix: | syn_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration