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v3.23.1

Non-controlling Interest and Related Party (Details) - USD ($) |  | 3 Months Ended | 6 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Sep. 05, 2018 | Sep. 30, 2022 | Jun. 30, 2022 | Jun. 30, 2022 | Sep. 30, 2022 | Dec. 31, 2022 | Dec. 31, 2021
Noncontrolling Interest |  |  |  |  |  |  |
Net loss attributable to non-controlling interest |  |  |  |  |  | $ 0 | $ (1,000)
Research and development expense |  | $ 2,570,000 | $ 3,485,000 | $ 6,082,000 | $ 8,652,000 | 11,723,000 | 7,800,000
Stock Purchase Agreement |  |  |  |  |  |  |
Noncontrolling Interest |  |  |  |  |  |  |
Research and development expense |  |  |  |  |  | $ 0 | $ 1,000
SYN Biomics |  |  |  |  |  |  |
Noncontrolling Interest |  |  |  |  |  |  |
Ownership percentage |  |  |  |  |  | 100.00% |
SYN Biomics | SYN Biomics |  |  |  |  |  |  |
Noncontrolling Interest |  |  |  |  |  |  |
Ownership percentage | 88.50% |  |  |  |  |  | 100.00%
Cedars-Sinai Medical Center |  |  |  |  |  |  |
Noncontrolling Interest |  |  |  |  |  |  |
Expenses from transactions with related party | $ 328,000 |  |  |  |  |  |
Fair value of shares issued | $ 285,000 |  |  |  |  |  |
Cedars-Sinai Medical Center | Stock Purchase Agreement |  |  |  |  |  |  |
Noncontrolling Interest |  |  |  |  |  |  |
Number of common stock, shares to be issued | 50,000 |  |  |  |  |  |
Cedars-Sinai Medical Center | SYN Biomics | Stock Purchase Agreement |  |  |  |  |  |  |
Noncontrolling Interest |  |  |  |  |  |  |
Additional number of common stock, shares to be issued | 2,420,000 |  |  |  |  |  |
Number of common stock, shares to be held by related party | 7,480,000 |  |  |  |  |  |
Noncontrolling interest, ownership percentage by noncontrolling owners | 17.00% |  |  |  |  |  |

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