The amount of additional cash payment for license agreement.

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Description related to additional consideration payable.

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Amounts incurred by the company under the of collaborative arrangements.

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Amount of estimated research services cost provided.

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Amount of annual payments due under the license agreement.

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Amount of the final payment due under the license agreement.

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Number of years within which payment has to be made under the agreement

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- Definition

A milestone payment is an authority payment made to a contractor which is linked to the contractor delivering a service or commodity such that, should the agreement be terminated at the point of payment.

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The amount of non cash addition to right of use assets.

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No definition available.

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It Represents options to be received common stock shares reporting period.

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The amount paid for the extension of option period.

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The amount of payment of option fee during the reporting period.

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Amount to be paid under the agreement after the clinical trials

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- Definition

Payment to be made to the foundation subject to private or public economic aid that third parties may grant to the institution.

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No definition available.

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- Definition

The amount of research and development costs incurred for a fixed-price, all payable in quarterly installments.

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No definition available.

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- Definition

The number of shares issued during the period for license agreement.

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No definition available.

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Amount of commitment made to pay deferred cash remuneration.

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No definition available.

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Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability.

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Amount of cash outflow for fees classified as other.

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Payments of cash to employees, including wages and salaries, during the current period.

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Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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Gross number of share options (or share units) granted during the period.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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License, Collaborative and Employment Agreements and Commitments (Details)								1 Months Ended		12 Months Ended
	Dec. 13, 2024 USD ($)	Dec. 14, 2023 USD ($) shares	Dec. 15, 2022 USD ($) shares	Aug. 07, 2019 USD ($)	Feb. 15, 2016 EUR (€)	Dec. 19, 2012 USD ($)	Nov. 28, 2012 USD ($) shares	Jan. 31, 2023 USD ($)	Nov. 30, 2017 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2023 EUR (€)	Dec. 31, 2022 USD ($)	Dec. 31, 2015 shares
License, Collaborative and Employment Agreements and Commitments
Annual base salary	$ 667,536	$ 644,963	$ 614,250
Operating lease cost										$ 631,000	$ 624,000
Non cash addition of right of use assets										937,000
Saint Joan de deu collaboration and license agreement
License, Collaborative and Employment Agreements and Commitments
Payment to be made subject to third party economic aid \| €					€ 500,000
Payment to be made after clinical trial \| €					€ 320,000
Maximum period for payment clinical trial					4 years
Licensing Agreements
License, Collaborative and Employment Agreements and Commitments
Annual payments due under license agreement						$ 50,000
Final payment due under license agreement						25,000
Steven A. Shallcross
License, Collaborative and Employment Agreements and Commitments
Cash bonus paid as per employee agreement	$ 200,000	$ 350,000	$ 385,000
Share-based payment award, options, grants in period, gross \| shares		700,000	475,000
Prev Abr Llc
License, Collaborative and Employment Agreements and Commitments
Additional cash payment for license agreement							$ 235,000
Unregistered shares issued to license agreement \| shares							17,858
Additional consideration payable							50% in cash and 50% in the Company’s stock
Options to be received common stock shares \| shares														18,724
Phase I Clinical Trials
License, Collaborative and Employment Agreements and Commitments
Milestone payment						50,000
Phase III Clinical Trials
License, Collaborative and Employment Agreements and Commitments
Milestone payment						100,000
NDA Submission In US
License, Collaborative and Employment Agreements and Commitments
Milestone payment						250,000
European Medicines Agency Approval
License, Collaborative and Employment Agreements and Commitments
Milestone payment						100,000
Regulatory Approval In Asian Country
License, Collaborative and Employment Agreements and Commitments
Milestone payment						100,000
Clinical Trial Agreement
License, Collaborative and Employment Agreements and Commitments
Estimated research costs				$ 3,200,000
Payments for other fees													$ 1,100,000
Exclusive Option License Agreement
License, Collaborative and Employment Agreements and Commitments
Extend option period								$ 7,500
Collaboration and license agreement \| Saint Joan de deu collaboration and license agreement
License, Collaborative and Employment Agreements and Commitments
Payment of option Fee \| €												€ 25,000
Technology Transfer Agreement
License, Collaborative and Employment Agreements and Commitments
Amounts incurred for termination of agreement										0	0
ICO Marketing License
License, Collaborative and Employment Agreements and Commitments
Amounts incurred for termination of agreement										0	0
IDIBELL/ICO License Agreement
License, Collaborative and Employment Agreements and Commitments
Amounts incurred for termination of agreement										0	0
University of Texas Austin Agreement
License, Collaborative and Employment Agreements and Commitments
Amounts incurred for termination of agreement										0	0
Consulting Fees
License, Collaborative and Employment Agreements and Commitments
Amounts incurred for termination of agreement										$ 0	$ 0
Payments for other fees									$ 4,500,000
First Year
License, Collaborative and Employment Agreements and Commitments
Research agreement fixed fee						303,000
Second Year
License, Collaborative and Employment Agreements and Commitments
Research agreement fixed fee						316,000
Third Year
License, Collaborative and Employment Agreements and Commitments
Research agreement fixed fee						$ 329,000