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    <element id="NITO_LoanAndPartnershipAgreementMember" name="LoanAndPartnershipAgreementMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_FinancingIncomeExpensesNet" name="FinancingIncomeExpensesNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_StockIssuedDuringPeriodValueExchangeAgreement" name="StockIssuedDuringPeriodValueExchangeAgreement" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_StockIssuedDuringPeriodSharesExchangeAgreement" name="StockIssuedDuringPeriodSharesExchangeAgreement" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_GainFromStandbyEquityPurchaseAgreementI" name="GainFromStandbyEquityPurchaseAgreementI" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_ExpensesFromStandbyEquityPurchaseAgreementIiAndPromissoryNote" name="ExpensesFromStandbyEquityPurchaseAgreementIiAndPromissoryNote" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_IncreaseDecreaseInExchangeRateDifferencesOnOperatingLeases" name="IncreaseDecreaseInExchangeRateDifferencesOnOperatingLeases" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_IncreaseDecreaseInOperatingLeaseExpense" name="IncreaseDecreaseInOperatingLeaseExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_ProceedsFromStandbyEquityPurchaseAgreementNet" name="ProceedsFromStandbyEquityPurchaseAgreementNet" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_InvestmentInNonconsolidatedAffiliate" name="InvestmentInNonconsolidatedAffiliate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_ScheduleOfChangesInFairValueOfAssetsTableTextBlock" name="ScheduleOfChangesInFairValueOfAssetsTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_ChangesInFairValueOfAssets" name="ChangesInFairValueOfAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisCreditFacilityToPlantify" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisCreditFacilityToPlantify" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_EquitySecuritiesFvNiMeasurementInputTerm" name="EquitySecuritiesFvNiMeasurementInputTerm" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_IncreaseInPercentageOfOwnership" name="IncreaseInPercentageOfOwnership" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_DebtInstrumentInvestmentRate" name="DebtInstrumentInvestmentRate" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_DebtInvestmenShares" name="DebtInvestmenShares" nillable="true" xbrli:periodType="instant" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_SharesAggregatePurchaseAmount" name="SharesAggregatePurchaseAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_PreAdvanceForPurchaseOfShares" name="PreAdvanceForPurchaseOfShares" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_StructuringFee" name="StructuringFee" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_DebtInstrumentDefaultInterestRatePercentage" name="DebtInstrumentDefaultInterestRatePercentage" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_UnallocatedCosts" name="UnallocatedCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_FinancingIncomeNet" name="FinancingIncomeNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="NITO_ExpensesFromStandbyEquityPurchaseAgreementII" name="ExpensesFromStandbyEquityPurchaseAgreementII" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
</schema>
