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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($)
 3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Income Statement [Abstract]        
Net product revenue $ 586,134 $ 0 $ 698,819 $ 0
Other revenue 12,940 0 12,940 0
Total revenue 599,074 0 711,759 0
Costs and expenses:        
Cost of product revenue 221,090 0 529,041 0
Research and development 5,665,357 3,445,200 16,147,357 9,440,324
Selling, general and administrative 5,447,847 4,722,281 15,937,326 11,842,896
Total costs and expenses 11,334,294 8,167,481 32,613,724 21,283,220
Loss from operations (10,735,220) (8,167,481) (31,901,965) (21,283,220)
Interest income, net 97,726 14,637 308,877 34,397
Net loss (10,637,494) (8,152,844) (31,593,088) (21,248,823)
Net loss attributable to common stockholders $ (10,637,494) $ (8,152,844) $ (31,593,088) $ (21,248,823)
Net loss per share attributable to common stockholders - basic and diluted (in usd per share) $ (0.65) $ (0.53) $ (1.96) $ (1.57)
Weighted-average number of common shares outstanding — basic and diluted (in shares) 16,361,617 15,290,435 16,104,510 13,520,438