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Basis of presentation and significant accounting policies (Tables)
12 Months Ended
Dec. 31, 2018
Accounting Policies [Abstract]  
Schedule of Depreciation over estimated useful life

Depreciation is provided over the following estimated useful lives:

 

Asset classification

  

Useful life

Furniture and equipment

   5 years

Laboratory equipment

   5 years

Leasehold improvements

   Remaining life of the lease