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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001032210-00-002416.txt : 20010101
<SEC-HEADER>0001032210-00-002416.hdr.sgml : 20010101
ACCESSION NUMBER:		0001032210-00-002416
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20001214
ITEM INFORMATION:		
ITEM INFORMATION:		
FILED AS OF DATE:		20001229

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OXIS INTERNATIONAL INC
		CENTRAL INDEX KEY:			0000109657
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				941620407
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		
		SEC FILE NUMBER:	000-08092
		FILM NUMBER:		798775

	BUSINESS ADDRESS:	
		STREET 1:		6040 N CUTTER CIRCLE STE 317
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97217
		BUSINESS PHONE:		5032833911

	MAIL ADDRESS:	
		STREET 1:		6040 N CUTTER CIRCLE STE 317
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97217

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DDI PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DIAGNOSTIC DATA INC /DE/
		DATE OF NAME CHANGE:	19850312
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>0001.txt
<DESCRIPTION>FORM 8-K
<TEXT>

<PAGE>

                      SECURITIES AND EXCHANGE COMMISSION

                            Washington, D.C. 20549
                               -----------------

                                   FORM 8-K

                                CURRENT REPORT

                      Pursuant to Section 13 or 15(d) of
                      the Securities Exchange Act of 1934

               Date of Report (Date of earliest event reported):

                               December 14, 2000

                               -----------------

                           OXIS INTERNATIONAL, INC.
              (Exact name of Registrant as specified in charter)

       Delaware                        0-8092                     94-1620407
(State or other jurisdiction     (Commission File No.)       (IRS Employer
    of incorporation)                                        Identification No.)

           6040 N. Cutter Circle, Suite 317, Portland, Oregon 97217
        (Address of principal executive offices)            (Zip Code)

      Registrant's telephone number, including area code:  (503) 283-3911

                                Not applicable
         (Former name or former address, if changed since last report)
<PAGE>

Item 5.  Other Events.

     The common stock, $0.001 par value (the "Common Stock"), of OXIS
International, Inc. (the "Company") is currently listed on the Nasdaq National
Market System.

     Nasdaq notified the Company on December 14, 2000 that because the minimum
bid price of the Common Stock has remained under $1.00 for 30 consecutive
trading days, the Common Stock does not currently meet Nasdaq's requirements for
continued listing on the Nasdaq National Market System. Consequently, if the bid
price of the Common Stock is not at least $1.00 for a minimum of ten consecutive
trading days before March 14, 2001, the Common Stock will become the subject of
a delisting notification from the Nasdaq National Market System. If the
Company's stock does not then satisfy the Nasdaq listing requirements, the
Company may seek review of the Nasdaq decision to de-list its stock. There can
be no assurance that the Company's Common Stock will satisfy the requirements
for continued listing on the Nasdaq National Market System, or that other
alternatives will be available, in which case, the Company's Common Stock would
be traded on the over-the-counter market.

     As discussed in the other filings, the Company will need additional
financing within the next twelve months. It may be more difficult for the
Company to raise additional financing if the Common Stock is delisted from the
Nasdaq National Market System, particularly if the Common Stock is reduced to
trading on the over-the-counter market. Delisting from the Nasdaq National
Market System may also adversely affect the market price and liquidity of the
Common Stock and may subject the Common Stock to the "penny stock rules"
contained in Section 15(g) of the Securities Exchange Act of 1934, as amended,
and the rules promulgated thereunder. A copy of the letter addressed to the
Company dated December 14, 2000 from Nasdaq, including any exhibits thereto, is
included as Exhibit 99.1. Such letter is incorporated by reference into this
Item 5.


Item 7.  Financial Statements and Exhibits.

     (c)  Exhibits.

          The following exhibits are filed herewith:

          99.1  Letter addressed to the Company dated December 14, 2000 from
          Nasdaq warning of delisting action.


                                  SIGNATURES

        Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

                                          OXIS INTERNATIONAL, INC.
                                          (Registrant)


     Dated: December 28, 2000             By: /s/ Jon S. Pitcher
                                             ----------------------------------
                                              Jon S. Pitcher
                                              Vice President and Chief Financial
                                              Officer

                                       2
<PAGE>

                                 EXHIBIT INDEX


<TABLE>
<CAPTION>
                                                                                 Page No. in
                                                                            sequentially numbered
Exhibit No.     Description                                                     current report
- -----------     -----------                                                     --------------
<S>              <C>                                                          <C>
99.1             Letter addressed to the Company dated December 14, 2000              4
                  from Nasdaq warning of delisting action
</TABLE>

                                       3
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>0002.txt
<DESCRIPTION>LETTER TO THE CO. FROM NASDAQ WARNING OF DELISTING
<TEXT>

<PAGE>

                                 EXHIBIT 99.1

                            [On NASDAQ Letterhead]


By Facsimile and First Class Mail

December 14, 2000

Mr. Jon S. Pitcher
Chief Financial Officer
OXIS International, Inc.
6040 N. Cutter Circle, Ste. 317
Portland, Oregon  97217-3935

Re:  OXIS International, Inc. (the "Company")

Dear Mr. Pitcher:

The Company's common stock has failed to maintain a minimum bid price of $1.00
over the last 30 consecutive trading days as required by Marketplace Rule
4450(a)(5) (the "Rule")./1/ Therefore, in accordance with Marketplace Rule
4310(c)(8)(B), the Company will be provided 90 calendar days, or until March 14,
2001, to regain compliance with this Rule./2/ If at anytime before March 14,
2001, the bid price of the Company's common stock is at least $1.00 for a
minimum of 10 consecutive trading days, Staff will determine if the Company
complies with the Rule. However, if the Company is unable to demonstrate
compliance with the Rule on or before March 14, 2001, Nasdaq will provide the
Company with written notification pursuant to Marketplace Rule 4815(a) that
Staff has determined to delist its common stock. At that time, the Company may
request a review of Staff's determination pursuant to Marketplace Rule 4800
Series.

If you have any questions concerning the compliance issues discussed above,
please contact Janel McBain, Senior Analyst at (301) 978-8045.

Sincerely,

/s/ Timothy J. Malinowski

Timothy J. Malinowski
Associate Director
Nasdaq Listing Qualifications

- ------------------------------
/1/  The Company also does not meet the maintenance requirements under
     Maintenance Standard 2. See attached chart.

/2/  The 90 day period related exclusively to the bid price deficiency. The
     Company may be delisted during the 90 day period for failure to maintain
     compliance with any other listing requirement for which it is currently on
     notice or which occurs during the period.

         The Nasdaq Stock Market, Inc., an NASD Company 9801 Washingtonian
         Blvd., Gaithersburg, MD 20878 877 536 2737

                                       4
<PAGE>

                            NASDAQ NATIONAL MARKET
                       CONTINUED INCLUSION REQUIREMENTS

The following table identifies the National Market maintenance standards.  Each
incidence of non-compliance is denoted with an "X".

COMPANY SYMBOL:  OXIS

<TABLE>
<S>                       <C>                          <C>      <C>                         <C>
                            Maintenance Standard                 Maintenance Standard
      Standards                       1                                   2
- -------------------------------------------------------------------------------------------------
Net Tangible Assets/3/           $4 million                              N/A
- -------------------------------------------------------------------------------------------------
Market Capitalization              N/A                               $50 million             X
                                                                         OR
Total Assets                                                        ($50 million
                                                                        AND
Total Revenue                                                        $50 million)
- -------------------------------------------------------------------------------------------------
Public Float (shares)/4/           750,000                           1.1 million
- -------------------------------------------------------------------------------------------------
Market Value of                   $5 million                         $15 million
Public Float
- -------------------------------------------------------------------------------------------------
Bid Price                            $1                 X                $5                  X
- -------------------------------------------------------------------------------------------------
Round Lot                            400                                 400
Shareholders/5/
- -------------------------------------------------------------------------------------------------
Market Makers/6/                      2                                   4
- -------------------------------------------------------------------------------------------------
Corporate Governance                 Yes                                 Yes
- -------------------------------------------------------------------------------------------------
</TABLE>

/3/  Net Tangible Assets = Total Assets - Total Liabilities - Goodwill -
     Redeemable Securities

/4/  Public float is defined as total shares outstanding less any shares held by
     officers, directors, or beneficial owners of 10 percent or more.

/5/  Round lot holders are holders of 100 shares or more.

/6/  An Electronic Communication Network ("ECN") is not considered an active
     market maker.

                                       5
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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