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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001144204-06-006593.txt : 20060215
<SEC-HEADER>0001144204-06-006593.hdr.sgml : 20060215
<ACCEPTANCE-DATETIME>20060215163904
ACCESSION NUMBER:		0001144204-06-006593
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20060202
ITEM INFORMATION:		Entry into a Material Definitive Agreement
ITEM INFORMATION:		Termination of a Material Definitive Agreement
FILED AS OF DATE:		20060215
DATE AS OF CHANGE:		20060215

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OXIS INTERNATIONAL INC
		CENTRAL INDEX KEY:			0000109657
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				941620407
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-08092
		FILM NUMBER:		06622282

	BUSINESS ADDRESS:	
		STREET 1:		6040 N CUTTER CIRCLE STE 317
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97217
		BUSINESS PHONE:		5032833911

	MAIL ADDRESS:	
		STREET 1:		6040 N CUTTER CIRCLE STE 317
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97217

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DDI PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DIAGNOSTIC DATA INC /DE/
		DATE OF NAME CHANGE:	19850312
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      agreement with an effective date of February 2, 2006 under similar terms to
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      As with
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      7, 2006, OXIS terminated its one-year non-revolving loan agreement with KeyBank
      National Association (&#8220;KeyBank&#8221;). The original loan agreement with KeyBank dated
      December 2, 2005 involved a loan in the amount of $3,060,000 (the &#8220;KeyBank
      Loan&#8221;) which OXIS utilized to purchase fifty one percent of the outstanding
      shares of BioCheck, Inc. Under the terms of the KeyBank Loan, </font><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">as
      security for OXIS' repayment obligations under the Loan Agreement, OXIS granted
      a security interest to KeyBank in a $3,060,000 Certificate of Deposit that
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      greater than the annual rate of interest on the Certificate of Deposit held
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      </strong></font></div>
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      has
      duly caused this Report to be signed on its behalf by the Undersigned hereunto
      duly authorized. </font></div>
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            <td width="3%"><font size="2">By:</font><font id="TAB2" style="COLOR: black; LETTER-SPACING: 27pt">&#160;</font></td>
            <td width="33%"><u><font size="2">/s/ Michael D.
              Centron&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;
              </font></u></td>
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            <td width="33%">&#160;</td>
            <td width="3%">&#160;</td>
            <td width="33%">
              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Michael
                D. Centron</font></div>
            </td>
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          <tr bgcolor="white">
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            <td width="3%">&#160;</td>
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              <div style="DISPLAY: block; MARGIN-LEFT: 0pt; TEXT-INDENT: 0pt; LINE-HEIGHT: 1.25; MARGIN-RIGHT: 0pt" align="left"><font style="DISPLAY: inline; FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman">Vice
                President &amp; Chief Financial
                Officer</font></div>
            </td>
          </tr>

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