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v3.22.1

Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited) - USD ($) $ in Thousands | Preferred Stock [Member] | Common Stock [Member] | Common Shares Issuable [Member] | Additional Paid-in Capital [Member] | Retained Earnings [Member] | Total
--- | --- | --- | --- | --- | --- | ---
Beginning balance, value at Dec. 31, 2020 | $ 3 | $ 5 |  | $ 566,356 | $ (595,797) | $ (29,433)
Beginning balance, shares at Dec. 31, 2020 | 2,450,000 | 5,218,000 |  |  |  |
Equity compensation to officers and board of directors |  | $ 4 |  | 14,292 |  | 14,296
Equity compensation to officers and board of directors, shares |  | 3,641,000 |  |  |  |
Issuance of common stock for services |  | $ 2 |  | 8,450 |  | 8,452
Issuance of common stock for services, shares |  | 1,957,000 |  |  |  |
Extinguishment of debt discount upon adoption of ASU 2020-06 |  |  |  | (4,745) | 226 | (4,519)
Conversion of Preferred Series J-1 to common stock | $ (2) | $ 1 |  | 1 |  |
Conversion of Preferred Series J-1 to common stock, Shares | (2,354,000) | 692,000 |  |  |  |
Common shares issued upon mandatory conversion of notes payable and accrued interest |  | $ 4 | $ 25,956 | 12,846 |  | 38,806
Common shares issued upon mandatory conversion of notes payable and accrued interest, Shares |  | 3,779,000 | 7,634,000 |  |  |
Common shares issued upon exercise of warrants |  |  |  | 58 |  | 58
Common shares issued upon exercise of warrants, Shares |  | 95,000 |  |  |  |
Issuance of common stock in public offering, net of cost |  | $ 5 |  | 24,674 |  | 24,679
Issuance of common stock in public offering, net of cost, Shares |  | 4,945,000 |  |  |  |
Issuance of common stock for research and development agreement |  |  |  | 1,355 |  | 1,355
Issuance of common stock for research and development agreement, Shares |  | 190,000 |  |  |  |
Net loss |  |  |  |  | (29,677) | (29,677)
Ending balance, value at Mar. 31, 2021 | $ 1 | $ 21 | $ 25,956 | 623,287 | (625,248) | 24,017
Ending balance, shares at Mar. 31, 2021 | 96,000 | 20,517,000 | 7,634,000 |  |  |
Beginning balance, value at Dec. 31, 2021 | $ 1 | $ 32 | $ 1,113 | 674,348 | (653,584) | 21,910
Beginning balance, shares at Dec. 31, 2021 | 96,000 | 32,062 | 327,000 |  |  |
Cancellation of common stock |  |  |  |  |  |
Cancellation of common stock, shares |  | (291) |  |  |  |
Issuance of common shares for common shares issuable |  |  | $ (1,113) | 1,113 |  |
Issuance of common shares as equity, shares |  | 327 |  |  |  |
Stock Issued During Period, Shares, Conversion of Convertible Securities |  |  | (327,000) |  |  |
Equity compensation to officers and board of directors |  |  |  | 447 |  | 447
Equity compensation to officers and board of directors, shares |  | 85,000 |  |  |  |
Issuance of common stock for services |  |  |  | 872 |  | 872
Issuance of common stock for services, shares |  | 163,000 |  |  |  |
Net loss |  |  |  |  | (5,440) | (5,440)
Ending balance, value at Mar. 31, 2022 | $ 1 | $ 32 |  | $ 676,780 | $ (659,024) | $ 17,789
Ending balance, shares at Mar. 31, 2022 | 96,000 | 32,346,000 |  |  |  |

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