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v3.22.2.2

Relationship with Parent and Related Entities - Additional Information (Details) - USD ($) |  |  |  | 3 Months Ended | 8 Months Ended | 9 Months Ended | 11 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Aug. 12, 2021 | Jun. 23, 2021 | Mar. 22, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Dec. 31, 2021 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Mar. 14, 2022 | Feb. 12, 2021
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-Based Payment Arrangement, Expense |  |  |  | $ 5,279,000 | $ 3,810,000 |  | $ 12,273,000 | $ 11,606,000 |  |  |  |  |  |
Research and Development Expense [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-Based Payment Arrangement, Expense |  |  |  | 3,079,000 | 2,395,000 |  | 7,243,000 | 6,902,000 |  |  |  |  |  |
General and Administrative Expense [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-Based Payment Arrangement, Expense |  |  |  | 2,200,000 | 1,415,000 |  | $ 5,030,000 | 4,704,000 |  |  |  |  |  |
Equity Based Incentive Plans [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-Based Payment Arrangement, Expense |  |  |  |  |  |  |  |  |  | $ 15,100,000 | $ 9,200,000 | $ 6,700,000 |  |
Equity Based Incentive Plans [Member] | Research and Development Expense [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-Based Payment Arrangement, Expense |  |  |  |  |  |  |  |  |  | 9,000,000 | 5,600,000 | 3,900,000 |  |
Equity Based Incentive Plans [Member] | General and Administrative Expense [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-Based Payment Arrangement, Expense |  |  |  |  |  |  |  |  |  | $ 6,100,000 | 3,600,000 | 2,800,000 |  |
Employee Stock Purchase Plan [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase price of common stock expressed as a percentage of its fair value |  |  |  |  |  |  |  |  |  | 85.00% |  |  |  |
Payments for repurchase of common stock |  |  |  |  |  |  |  |  |  | $ 25,000,000 |  |  |  |
Percentage of their eligible compensation during the offering period. |  |  |  |  |  |  |  |  |  | 10.00% |  |  |  |
Share-Based Payment Arrangement, Expense |  |  |  |  |  |  |  |  |  | $ 200 | 100 | 100 |  |
Maximum [Member] | Equity Based Incentive Plans [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based compensation arrangement by share-based payment award, terms of award |  |  |  |  |  |  | 1/48 each month thereafter for forty-two months |  |  | 1/48 each month thereafter for forty-two months |  |  |  |
Minimum [Member] | Equity Based Incentive Plans [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based compensation arrangement by share-based payment award, terms of award |  |  |  |  |  |  | 1/8 on the six month |  |  | 1/8 on the six month |  |  |  |
Avista Public Acquisition Corp. II [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from promissory note - related party |  |  |  |  |  | $ 119,275 | $ 0 |  | $ 175,000 |  |  |  |  |
Repayment of related party promissory note |  |  |  |  |  | 175,000 | 0 |  |  |  |  |  |  |
Promissory Note with Related Party | Avista Public Acquisition Corp. II [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum borrowing capacity of related party promissory note |  |  |  |  |  |  |  |  | 300,000 | $ 300,000 |  |  |  | $ 300,000
Offering costs paid by Sponsor and included in promissory note - related party |  |  | $ 55,725 |  |  |  |  |  |  |  |  |  |  |
Proceeds from promissory note - related party |  | $ 119,275 |  |  |  |  |  |  |  |  |  |  |  |
Repayment of related party promissory note | $ 175,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Administrative Support Agreement | Avista Public Acquisition Corp. II [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Expenses per month |  |  |  |  |  |  | 10,000 |  | 10,000 |  |  |  |  |
Expenses incurred and paid |  |  |  | 30,000 |  | $ 20,000 | 90,000 |  | 46,129 |  |  |  |  |
Related Party Loans | Avista Public Acquisition Corp. II [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum borrowing capacity of related party promissory note |  |  |  | 750,000 |  |  | 750,000 |  |  |  |  |  | $ 750,000 |
Loan conversion agreement warrant |  |  |  | $ 2,000,000 |  |  | $ 2,000,000 |  | $ 2,000,000 | $ 2,000,000 |  |  |  |
Price of warrant |  |  |  | $ 1.5 |  |  | $ 1.5 |  | $ 1.5 | $ 1.5 |  |  | $ 1.5 |
Working capital loans, outstanding |  |  |  | $ 750,000 |  |  | $ 750,000 |  | $ 0 | $ 0 |  |  |  |
Service [Member] | Director [Member] | Avista Public Acquisition Corp. II [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Service fee paid to a director |  |  |  |  |  |  | 10,000 |  |  |  |  |  |  |
General Corporate Overhead [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Selling, general and administrative expenses from transactions with related party |  |  |  | $ 1,600,000 | $ 900,000 |  | $ 4,900,000 | $ 3,800,000 |  | $ 6,100 | $ 3,600 | $ 2,800 |  |

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