Balance Sheet Account Details

9 Months Ended

12 Months Ended

Sep. 30, 2022

Dec. 31, 2021

Balance Sheet Account Details [Abstract]

Balance Sheet Account Details

7. Balance Sheet Account Details

Property and equipment

Property and equipment are stated at cost and consist of the following (in thousands):


	September 30, 2022			December 31, 2021
Lab and office equipment	$	6,443		$	6,410
Leasehold improvements		17,639			3,495
Computer equipment and software		487			182

		24,569			10,087
Less: accumulated depreciation and amortization		(5,194	)		(3,292	)

Total property and equipment, net	$	19,375		$	6,795

Depreciation of equipment is computed using the straight-line method over the estimated useful lives of the assets which range from three to ten years. Leasehold improvements are amortized using the straight-line method over their estimated useful lives or their related lease term, whichever is shorter. Depreciation expense for the three and nine months ended September 30, 2022 was $0.7 million and $1.9 million, respectfully. Depreciation expense for the three and nine months ended September 30, 2021 was $0.4 million and $1.0 million, respectively.

Goodwill and identifiable intangible assets

Goodwill and other identifiable intangible assets consist of the following (in thousands):


	September 30, 2022			December 31, 2021
Indefinite-lived intangible assets
Goodwill	$	83,979		$	83,979
Definite lived intangible assets
Complete technology		227,129			227,403
Less: accumulated amortization		(68,980	)		(60,099	)
Customer relationships		11,100			11,100
Less: accumulated amortization		(2,975	)		(2,083	)

Total goodwill and other identifiable intangible assets, net	$	250,253		$	260,300

Amortization of finite-lived intangible assets is computed using the straight-line method over the estimated useful life of the asset of up to 20 years. Amortization expense for the three and nine months ended September 30, 2022 was $3.3 million and $9.8 million, respectively. Amortization expense for the three and nine months ended September 30, 2021 was $3.3 million and $9.7 million, respectively.

Accrued Liabilities

Accrued liabilities consist of the following (in thousands):


	September 30, 2022		December 31, 2021
Compensation	$	2,249	$	2,320
Professional fees		1,679		67
Royalties owed to third parties		124		296
Acquisition related liabilities		—		1,000
Other		40		63

Total accrued liabilities	$	4,092	$	3,746

7. Balance Sheet Account Details

Property and equipment are stated at cost and consist of the following (in thousands):


	December 31,
	2021			2020
Lab and office equipment	$	6,410		$	3,872
Leasehold improvements		3,495			732
Computer equipment and software		182			182

		10,087			4,786
Less accumulated depreciation and amortization		(3,292	)		(1,306	)

	$	6,795		$	3,480

Depreciation of equipment is computed using the straight-line method over the estimated useful lives of the assets which range from three to
ten years. Leasehold improvements are amortized using the straight-line method over their estimated useful lives or their related lease term, whichever is
shorter. Depreciation expense of $2.0 million, $0.8 million and $0.3 million was recognized for the years ended December 31, 2021, 2020 and 2019,
respectively, and was included in operating expenses.

Goodwill and identifiable intangible assets consist of the following (in thousands):


	December 31,
	2021			2020
Indefinite-lived intangible assets
Goodwill	$	83,979		$	83,979
Definite-lived intangible assets
Complete technology		227,403			224,758
Less: Accumulated amortization		(60,099	)		(48,321	)
Customer relationships		11,100			11,100
Less: Accumulated amortization		(2,083	)		(893	)

Total goodwill and other identifiable intangible assets, net	$	260,300		$	270,623

Amortization of finite-lived intangible assets is computed using the straight-line method over the estimated useful life of the asset of up to 20 years. Amortization expense of $13.0 million, $11.8 million and $10.3 million was recognized for the years ended December 31, 2021, 2020 and 2019, respectively. Estimated amortization expense for the years ending December 31, 2022 through 2026 is $13.0 million per year. For each of the years ended December 31, 2021, 2020 and 2019, there was no impairment of intangible assets with finite lives.

Accrued liabilities consist of the following (in thousands):


	December 31,
	2021		2020
Compensation	$	2,320	$	1,495
Professional fees		67		22
Royalties owed to third parties		296		272
Subcontractor		—		482
Acquisitions related liabilities		1,000		1,500
Other		63		185

	$	3,746	$	3,956