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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
 3 Months Ended 8 Months Ended 9 Months Ended 11 Months Ended 12 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Revenues:                  
Revenues $ 6,910,000 $ 6,277,000   $ 23,732,000 $ 19,468,000   $ 34,748,000 $ 23,268,000 $ 18,318,000
Operating expenses:                  
Research and development 13,189,000 9,925,000   35,445,000 28,207,000   39,232,000 24,796,000 13,208,000
General and administrative 5,582,000 3,697,000   14,697,000 12,603,000   16,947,000 10,225,000 8,651,000
Amortization of intangibles 3,256,000 3,278,000   9,774,000 9,740,000   12,968,000 11,800,000 10,304,000
Other operating expense (income), net (208,000) (817,000)   (486,000) (546,000)   1,210,000 2,070,000 (818,000)
Total operating expenses 21,819,000 16,083,000   59,430,000 50,004,000   70,357,000 48,891,000 31,345,000
Loss from operations (14,909,000) (9,806,000)   (35,698,000) (30,536,000)   (35,609,000) (25,623,000) (13,027,000)
Other income (expense):                  
Total other income             1,259,000 1,895,000 0
Interest expense 0 0   0 (6,000)   (7,000) (5,000) 0
Other income, net             1,266,000 1,900,000 0
Loss before income tax (14,909,000) (9,806,000)   (35,698,000) (30,542,000)   (34,350,000) (23,728,000) (13,027,000)
Income tax benefit (expense) 2,313,000 1,916,000   6,544,000 6,572,000   7,308,000 6,171,000 (562,000)
Net loss (12,596,000) (7,890,000)   (29,154,000) (23,970,000)   (27,042,000) (17,557,000) (13,589,000)
Service [Member]                  
Revenues:                  
Revenues 4,928,000 4,877,000   14,922,000 14,254,000   20,084,000 11,883,000 5,568,000
License And Milestone Revenue [Member]                  
Revenues:                  
Revenues 1,400,000 1,400,000   7,826,000 5,214,000   $ 14,664,000 $ 11,385,000 $ 12,750,000
Royalty [Member]                  
Revenues:                  
Revenues 582,000 0   984,000 $ 0        
Avista Public Acquisition Corp. II [Member]                  
Operating expenses:                  
Formation and operating costs 2,344,863 170,579 $ 180,550 8,744,341   $ 516,442      
Loss from operations (2,344,863) (170,579) (180,550) (8,744,341)          
Other income (expense):                  
Gain on investments held in Trust Account 1,090,543 0 0 1,438,875          
Change in fair value of Forward Purchase and Backstop Securities (1,212,110) 0 0 (1,147,120)          
Net loss (2,466,430) (170,579) (180,550) (8,452,586)   $ (516,442)      
Deemed dividend - Forward Purchase and Backstop Securities 0 0 0 (225,000)          
Net loss attributable to ordinary shareholders $ (2,466,430) $ (170,579) $ (180,550) $ (8,677,586)          
Class A ordinary shares | Avista Public Acquisition Corp. II [Member]                  
Other income (expense):                  
Weighted average shares outstanding, basic 23,000,000 12,250,000 4,755,274 23,000,000   9,857,143      
Weighted average shares outstanding, diluted 23,000,000 12,250,000 4,755,274 23,000,000   9,857,143      
Basic net loss per ordinary share $ (0.09) $ (0.01) $ (0.02) $ (0.29)   $ (0.03)      
Diluted net loss per ordinary share $ (0.09) $ (0.01) $ (0.02) $ (0.29)   $ (0.03)      
Common Class B [Member] | Avista Public Acquisition Corp. II [Member]                  
Other income (expense):                  
Weighted average shares outstanding, basic 5,750,000 5,399,457 5,155,063 5,750,000   5,321,429      
Weighted average shares outstanding, diluted 5,750,000 5,399,457 5,155,063 5,750,000   5,321,429      
Basic net loss per ordinary share $ (0.09) $ (0.01) $ (0.02) $ (0.29)   $ (0.03)      
Diluted net loss per ordinary share $ (0.09) $ (0.01) $ (0.02) $ (0.29)   $ (0.03)