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Consolidated Statements of Changes in Equity - USD ($) $ in Thousands | Total | Share capital Subscription receipts and Public Offering Warrants | Equity component of convertible unsecured senior notes | Contributed surplus | Deficit | Accumulated other comprehensive income (loss)
--- | --- | --- | --- | --- | --- | ---
Beginning balance at Nov. 30, 2020 |  | $ 3,224 |  | $ 287,312 | $ 4,457 | $ 12,065 | $ (300,129) | $ (481)
Beginning balance, Shares at Nov. 30, 2020 | [1] |  |  | 19,253,360 |  |  |  |
Total comprehensive loss |  |  |  |  |  |  |  |
Net loss |  | (31,725) | [2] |  |  |  | (31,725) |
Other comprehensive income |  |  |  |  |  |  |  |
Net change in fair value of FVOCI financial assets |  | (197) |  |  |  |  |  | (197)
Exchange differences on translation of foreign operations |  | 634 |  |  |  |  |  | 634
Total comprehensive loss |  | (31,288) |  |  |  |  | (31,725) | 437
Transactions with owners, recorded directly in equity |  |  |  |  |  |  |  |
Public issue of common shares and warrants |  | 46,002 |  | $ 46,002 |  |  |  |
Public issue of common shares and warrants (Shares) | [1] |  |  | 4,181,975 |  |  |  |
Share issue costs |  | (3,394) |  |  |  |  | (3,394) |
Exercise of warrants (Shares) | [1] |  |  | 58,350 |  |  |  |
Exercise of warrants |  | 742 |  | $ 742 |  |  |  |
Share issue – Oncology |  |  |  | $ 668 |  | (668) |  |
Share issue – Oncology (Shares) | [1] |  |  | 120,482 |  |  |  |
Share-based compensation plan |  |  |  |  |  |  |  |
Share-based compensation for stock option plan |  | 1,879 |  |  |  | 1,879 |  |
Exercise of Options: |  |  |  |  |  |  |  |
Monetary consideration |  | 595 |  | $ 595 |  |  |  |
Monetary consideration Shares | [1] |  |  | 166,250 |  |  |  |
Attributed value |  |  |  | $ 433 |  | (433) |  |
Total contributions by owners |  | 45,824 |  | $ 48,440 |  | 778 | (3,394) |
Total contributions by owners shares | [1] |  |  | 4,527,057 |  |  |  |
Ending Balance at Nov. 30, 2021 |  | 17,760 |  | $ 335,752 | 4,457 | 12,843 | (335,248) | (44)
Ending Balance, Shares at Nov. 30, 2021 | [1] |  |  | 23,780,417 |  |  |  |
Total comprehensive loss |  |  |  |  |  |  |  |
Net loss |  | (47,237) |  |  |  |  | (47,237) |
Other comprehensive income |  |  |  |  |  |  |  |
Net change in fair value of FVOCI financial assets |  | (360) |  |  |  |  |  | (360)
Exchange differences on translation of foreign operations |  | 789 |  |  |  |  |  | 789
Total comprehensive loss |  | (46,808) |  |  |  |  | (47,237) | 429
Transactions with owners, recorded directly in equity |  |  |  |  |  |  |  |
Share issue costs |  | (164) |  |  |  |  | (164) |
Share issue - ATM program |  | 2,960 |  | $ 2,960 |  |  |  |
Share issue - ATM program (shares) | [1] |  |  | 400,000 |  |  |  |
Repurchase of convertible unsecured senior notes |  | (200) |  |  | (2,325) | 2,125 |  |
Share-based compensation plan |  |  |  |  |  |  |  |
Share-based compensation for stock option plan |  | 3,860 |  |  |  | 3,860 |  |
Exercise of Options: |  |  |  |  |  |  |  |
Monetary consideration |  | 21 |  | $ 21 |  |  |  |
Monetary consideration Shares | [1] |  |  | 21,165 |  |  |  |
Attributed value |  |  |  | $ 18 |  | (18) |  |
Total contributions by owners |  | 6,477 |  | $ 2,999 | (2,325) | 5,967 | (164) |
Total contributions by owners shares | [1] |  |  | 421,165 |  |  |  |
Ending Balance at Nov. 30, 2022 |  | (22,571) |  | $ 338,751 | 2,132 | 18,810 | (382,649) | 385
Ending Balance, Shares at Nov. 30, 2022 | [1] |  |  | 24,201,582 |  |  |  |
Total comprehensive loss |  |  |  |  |  |  |  |
Net loss |  | (23,957) |  |  |  |  | (23,957) |
Other comprehensive income |  |  |  |  |  |  |  |
Net change in fair value of FVOCI financial assets |  | 299 |  |  |  |  |  | 299
Exchange differences on translation of foreign operations |  | 0 |  |  |  |  |  |
Total comprehensive loss |  | (23,658) |  |  |  |  | (23,957) | 299
Transactions with owners, recorded directly in equity |  |  |  |  |  |  |  |
Share issue costs |  | (2,053) |  |  |  |  | (2,053) |
Public issue of common shares |  | 25,160 |  | $ 25,160 |  |  |  |
Public issue of common shares (Shares) | [1] |  |  | 21,778,184 |  |  |  |
Conversion of convertible unsecured senior notes |  | 15 |  | $ 16 | (1) |  |  |
Conversion of convertible unsecured senior notes (Shares) | [1] |  |  | 253 |  |  |  |
Repurchase of convertible unsecured senior notes |  | 0 |  |  | (2,131) | 2,131 |  |
Share-based compensation plan |  |  |  |  |  |  |  |
Share-based compensation for stock option plan |  | 2,237 |  |  |  | 2,237 |  |
Exercise of Options: |  |  |  |  |  |  |  |
Total contributions by owners |  | 25,359 |  | $ 25,176 | (2,132) | 4,368 | (2,053) |
Total contributions by owners shares | [1] |  |  | 21,778,437 |  |  |  |
Ending Balance at Nov. 30, 2023 |  | $ (20,870) |  | $ 363,927 | $ 0 | $ 23,178 | $ (408,659) | $ 684
Ending Balance, Shares at Nov. 30, 2023 | [1] |  |  | 45,980,019 |  |  |  |
[1] | See note 1 for share consolidation.
[2] | The company voluntarily changed its accounting policy to classify interest paid and received as part of operating activities, see Note 1.

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