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Property and equipment - Summary of information about property plant equipment (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Nov. 30, 2023
Nov. 30, 2022
Cost    
Beginning Balance $ 1,494  
Ending Balance 1,206 $ 1,494
Net carrying amounts    
Property and equipment 1,206 1,494
Cost    
Cost    
Beginning Balance 2,340 1,462
Additions 162 1,141
Disposals (46) (263)
Ending Balance 0 2,340
Net carrying amounts    
Property and equipment 0 2,340
Accumulated depreciation    
Accumulated depreciation    
Beginning Balance 846 719
Depreciation 450 390
Disposals (46) (263)
Ending Balance 1,250 846
Computer equipment    
Cost    
Beginning Balance 167  
Ending Balance 74 167
Net carrying amounts    
Property and equipment 74 167
Computer equipment | Cost    
Cost    
Beginning Balance 290 373
Additions 7 180
Disposals (46) (263)
Ending Balance 0 290
Net carrying amounts    
Property and equipment 0 290
Computer equipment | Accumulated depreciation    
Accumulated depreciation    
Beginning Balance 123 229
Depreciation 100 157
Disposals (46) (263)
Ending Balance 177 123
Laboratory equipment    
Cost    
Beginning Balance 905  
Ending Balance 816 905
Net carrying amounts    
Property and equipment 816 905
Laboratory equipment | Cost    
Cost    
Beginning Balance 1,068 107
Additions 128 961
Disposals 0 0
Ending Balance 0 1,068
Net carrying amounts    
Property and equipment 0 1,068
Laboratory equipment | Accumulated depreciation    
Accumulated depreciation    
Beginning Balance 163 69
Depreciation 217 94
Disposals 0 0
Ending Balance 380 163
Office furniture and equipment    
Cost    
Beginning Balance 137  
Ending Balance 132 137
Net carrying amounts    
Property and equipment 132 137
Office furniture and equipment | Cost    
Cost    
Beginning Balance 332 332
Additions 27 0
Disposals 0 0
Ending Balance 0 332
Net carrying amounts    
Property and equipment 0 332
Office furniture and equipment | Accumulated depreciation    
Accumulated depreciation    
Beginning Balance 195 157
Depreciation 32 38
Disposals 0 0
Ending Balance 227 195
Leasehold improvements    
Cost    
Beginning Balance 285  
Ending Balance 184 285
Net carrying amounts    
Property and equipment 184 285
Leasehold improvements | Cost    
Cost    
Beginning Balance 650 650
Additions 0 0
Disposals 0 0
Ending Balance 0 650
Net carrying amounts    
Property and equipment 0 650
Leasehold improvements | Accumulated depreciation    
Accumulated depreciation    
Beginning Balance 365 264
Depreciation 101 101
Disposals 0 0
Ending Balance $ 466 $ 365