<SEC-DOCUMENT>0001178913-22-000085.txt : 20220111
<SEC-HEADER>0001178913-22-000085.hdr.sgml : 20220111
<ACCEPTANCE-DATETIME>20220111160600
ACCESSION NUMBER:		0001178913-22-000085
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20220101
FILED AS OF DATE:		20220111
DATE AS OF CHANGE:		20220111

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LIEBERMAN GERALD M
		CENTRAL INDEX KEY:			0001234346

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38556
		FILM NUMBER:		22523939

	MAIL ADDRESS:	
		STREET 1:		C/O ALLIANCE CAPITAL
		STREET 2:		1345 AVENUE OF THE AMERICAS
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10105

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Entera Bio Ltd.
		CENTRAL INDEX KEY:			0001638097
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			L3
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		KIRYAT HADASSAH, MINRAV BUILDING
		STREET 2:		FIFTH FLOOR
		CITY:			JERUSALEM
		STATE:			L3
		ZIP:			9112002
		BUSINESS PHONE:		972-2-532-7151

	MAIL ADDRESS:	
		STREET 1:		KIRYAT HADASSAH, MINRAV BUILDING
		STREET 2:		FIFTH FLOOR
		CITY:			JERUSALEM
		STATE:			L3
		ZIP:			9112002
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
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<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2022-01-01</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001638097</issuerCik>
        <issuerName>Entera Bio Ltd.</issuerName>
        <issuerTradingSymbol>ENTX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001234346</rptOwnerCik>
            <rptOwnerName>LIEBERMAN GERALD M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>KIRYAT HADASSAH,</rptOwnerStreet1>
            <rptOwnerStreet2>MINRAV BUILDING, 5TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>JERUSALEM</rptOwnerCity>
            <rptOwnerState>L3</rptOwnerState>
            <rptOwnerZipCode>9112002</rptOwnerZipCode>
            <rptOwnerStateDescription>ISRAEL</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Ordinary Shares, par value NIS 0.0000769 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>131918</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.69</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2017-11-04</value>
            </exerciseDate>
            <expirationDate>
                <value>2023-04-06</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Ordinary Shares, par value NIS 0.0000769 per share</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>147290</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
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        <derivativeHolding>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.98</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2029-01-17</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Ordinary Shares, par value NIS 0.0000769 per share</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>33638</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The options vested ratably on a quarterly basis over a three-year period that commenced December 27, 2018.</footnote>
    </footnotes>

    <remarks>See Exhibit 24.1 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Dana Yaacov-Garbeli, Attorney-in-fact</signatureName>
        <signatureDate>2022-01-11</signatureDate>
    </ownerSignature>
</ownershipDocument>
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<DOCUMENT>
<TYPE>EX-24.1
<SEQUENCE>2
<FILENAME>exhibit_24-1.htm
<TEXT>
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    <div>
      <div style="text-align: right; line-height: 1.25; font-weight: bold;"><u>Exhibit 24.1</u></div>
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    <div>
      <div><br>
        <div>
          <div style="text-align: center; line-height: 1.25; font-weight: bold;">Power of Attorney</div>
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          </div>
          <div style="text-align: justify; line-height: 1.25;">KNOW ALL PERSONS BY THESE PRESENTS, that the undersigned hereby constitutes and appoints each and any of Dr. Spiros Jamas and Dana
            Yaacov-Garbeli his or her true and lawful attorney-in-fact and agent, with full power of substitution and re-substitution, for him or her and in his or her name, place and stead, in any and all capacities (until revoked in writing) to:</div>
          <div style="line-height: 1.25;"><br style="line-height: 1.25;">
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          <div style="text-align: justify; line-height: 1.25;">1.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Sign any and all
              instruments, certificates and documents appropriate or required to be executed on behalf of the undersigned with respect to the securities of&#160; Entera Bio Ltd., an Israeli company (the &#8220;Company&#8221;) pursuant to sections 13 and 16 of the
              Securities Exchange Act of 1934, as amended (the &#8220;Exchange Act&#8221;), and any and all regulations promulgated thereunder (including, without limitation, any Joint Filing Agreement with respect thereto), and to file the same, with all exhibits
              thereto, and any other documents in connection therewith, with the Securities and Exchange Commission (the &#8220;SEC&#8221;), and with any other entity when and if such is mandated by the Exchange Act or by the Bylaws of the Financial Industry
              Regulatory Authority;</div>
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          <div style="text-align: justify; line-height: 1.25;">2.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;prepare, execute,
              acknowledge, deliver and file a Form ID (including any amendments or authentications thereto) with respect to obtaining EDGAR codes, with the SEC;</div>
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          <div style="text-align: justify; line-height: 1.25;">3.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;seek or obtain, as
              the representative of the undersigned and on behalf of the undersigned, information on transactions in securities of the Company, from any third party, including brokers, employee benefit plan administrators and trustees, and the undersigned
              hereby authorizes any such person to release any such information to such attorneys-in-fact and the undersigned approves and ratifies any such release of information; and</div>
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          <div style="text-align: justify; line-height: 1.25;">4.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;perform any and all
              other acts which in the discretion of such attorneys-in-fact are necessary or desirable for and on behalf of the undersigned in connection with the foregoing.</div>
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          <div style="text-align: justify; line-height: 1.25;">The undersigned acknowledges that:</div>
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          <div style="text-align: justify; line-height: 1.25;">1.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;this Power of
              Attorney authorizes, but does not require, such attorneys-in-fact to act in their discretion on information provided to such attorneys-in-fact without independent verification of such information;</div>
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          <div style="text-align: justify; line-height: 1.25;">2.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;any documents
              prepared and/or executed by such attorneys-in-fact on behalf of any of the undersigned pursuant to this Power of Attorney will be in such form and will contain such information and disclosure as such attorney-in-fact, in his or her
              discretion, deems necessary or desirable;</div>
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          <div style="text-align: justify; line-height: 1.25;">3.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;the
              attorneys-in-fact do not assume (a) any liability for responsibility to comply with the requirements of the Exchange Act for any of the undersigned, (b) any liability for any failure to comply with such requirements for any of the
              undersigned, or (c) any obligation or liability for profit disgorgement under Section 16(b) of the Exchange Act for any of the undersigned; and</div>
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          </div>
          <div style="text-align: justify; line-height: 1.25;">4.&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;this Power of
              Attorney does not relieve any of the undersigned from responsibility for compliance with the undersigned&#8217;s obligations under the Exchange Act, including without limitation the reporting requirements under Sections 13 and 16 of the Exchange
              Act.</div>
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          <div style="text-align: justify; line-height: 1.25;">The undersigned hereby gives and grants the foregoing attorneys-in-fact full power and authority to do and perform all and every
            act and thing whatsoever requisite, necessary or appropriate to be done in and about the foregoing matters as fully to all intents and purposes as the undersigned might or could do if present, with full power of substitution and revocation,
            hereby ratifying all that such attorney-in-fact, or such attorney-in-fact&#8217;s substitute or substitutes, of, for and on behalf of the undersigned, shall lawfully do or cause to be done by virtue of this Power of Attorney.&#160; This Power of Attorney
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          <div style="text-align: center; line-height: 1.25;">[Signature page follows]</div>
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          <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 4th day of
            January, 2022.</div>
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                    <div style="line-height: 1.25;"><font style="font-family: 'Times New Roman',Times,serif;"><u>/s/ Gerald M. Lieberman</u></font>&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <br>
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                <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
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                    <div style="line-height: 1.25;">Gerald M. Lieberman</div>
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